Study of the Effect of General Anesthesia on Children's Behavior

NCT05164913 | Unknown

• 1 other identifier: SH9H-2019-T12
• Study Type: observational
• Target: 1,140
• Locations: 1 country
• Sites: 1

Brief Summary

This topic speculates that there is an interaction between family environment and anesthetic drug exposure on children's behavior. Different family environments have different response to anesthetic drug exposure. Children living in a specific family environment may be more susceptible to the effects of anesthetic drugs. People who are susceptible to exposure to narcotic drugs. In order to clarify this hypothesis and discover specific family environment factors that interact with anesthetic drug exposure, this project intends to establish a retrospective cohort study, through hierarchical analysis and other means, to clarify the behavioral changes of children in different family environments after exposure to anesthetic drugs. Provide theoretical support for the safe application of clinical children's anesthetics.

Conditions

Behavior

Outcome Measures

Primary Outcomes (1)

• Achenbach Child Behavior Checklist （CBCL）scale

  sorce（0-100），higher scores mean a worse

  immediately after the procedure

Study Arms (3)

Control group

No general anesthesia between 0-3 years old or 0-5 years old

Other: Achenbach Child Behavior Checklist （CBCL）scale

Single anesthesia group

Only once general anesthesia between 0-3 years old or 0-5 years old

Other: Achenbach Child Behavior Checklist （CBCL）scale

Multiple anesthesia group

More than once general anesthesia between 0-3 years old or 0-5 years old

Other: Achenbach Child Behavior Checklist （CBCL）scale

Interventions

Achenbach Child Behavior Checklist （CBCL）scale OTHER

Use the Achenbach Child Behavior Checklist （CBCL）scale to assess children's behavior

Control group; Multiple anesthesia group; Single anesthesia group

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children without basic behavioral abnormalities who have undergone surgery in this hospital

You may qualify if:

• Children aged 0-5 who underwent surgery at Shanghai Ninth People's Hospital
• Current age is less than 18 years old
• No surgical complications such as acute infectious diseases, systemic diseases

You may not qualify if:

• History of neonatal hypoxic ischemic encephalopathy and bilirubin encephalopathy
• There are genetic diseases or chromosomal diseases, neurological diseases (including epilepsy, congenital diseases), or a history of head trauma, a history of central nervous system infectious diseases, high fever convulsions, congenital heart disease, tumor diseases, and Patients with blood diseases
• People who have autism, attention deficit hyperactivity disorder, or have received behavioral related treatments and interventions
• Those who have undergone cardiovascular surgery, neurosurgery, or those with unstable hemodynamics during surgery
• Those who cannot be contacted, refused to join the group, the questionnaire information does not match the medical records, or the complete medical records cannot be obtained

Sponsors & Collaborators

• Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University: lead

Study Sites (1)

Shanghai Ninth People's Hospital

Shanghai, Shanghai Municipality, 200000, China

RECRUITING

MeSH Terms

Conditions

Behavior

Central Study Contacts

Ren Zhou

CONTACT

+8615121007303; 318281114@qq.com

Hong Jiang

CONTACT

jianghongjiuyuan@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 22, 2021
• First Posted: December 21, 2021
• Study Start: September 1, 2019
• Primary Completion: December 1, 2022
• Study Completion: January 1, 2023
• Last Updated: December 21, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)