NCT03726840

Brief Summary

The purpose of this study is to examine the effect of three specific odors on simulated driving performance. It is hypothesized that the presence of peppermint, rosemary, and zest/pulp will increase memory recall for navigation and improve reaction times for braking, compared to performance during unscented conditions

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 8, 2018

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

October 30, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 1, 2018

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2019

Completed
Last Updated

July 14, 2020

Status Verified

July 1, 2020

Enrollment Period

3 months

First QC Date

October 30, 2018

Last Update Submit

July 13, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Navigation Assessment

    The navigation task will consist of up to six blocks of instruction/recall segments that will contain the same number of turns over the same distance, but with novel environmental stimuli and a randomized order of turns unique to each block.

    30 minutes

Secondary Outcomes (3)

  • Braking Assessment

    15 minutes

  • Workload and mood assessment

    5 minutes

  • Scent assessment

    5 minutes

Study Arms (2)

Driving performance no fragrance

NO INTERVENTION

healthy young (ages 24-35 years) and older (ages 60-85 years) with no fragrance

Driving performance Fragrance

EXPERIMENTAL

healthy young (ages 24-35 years) and older (ages 60-85 years) with fragrance

Other: Fragrance

Interventions

peppermint, rosemary, and zest/pulp will increase memory recall for navigation and improve reaction times for braking, compared to performance during unscented conditions

Driving performance Fragrance

Eligibility Criteria

Age24 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • valid drivers license
  • normal or corrected to normal vision

You may not qualify if:

  • no drivers license
  • hyperopic vision without contact lenses
  • history of congenital or acquired cognitive, ophthalmologic, or neurological disorders including developmental delay, brain tumor, stroke, or known peripheral or central vestibular disorders
  • participants who have been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) will be excluded
  • Participants will also be excluded if they have: (a) a history of skin irritation or sensitivity to scented products or cosmetics, (b) known skin allergies, sensitive skin or allergies to fragrance, (c) suffers from a cold, allergy, sinus condition or any other condition that might interfere with their sense of smell and (d) is pregnant or nursing.
  • Participants will also be excluded if they smoke or use tobacco related products
  • participants will be excluded if they commonly experience motion sickness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cincinanti Childrens Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Location

MeSH Terms

Conditions

Behavior

Interventions

Odorants

Intervention Hierarchy (Ancestors)

EnvironmentEcological and Environmental PhenomenaBiological PhenomenaEnvironment and Public Health

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 30, 2018

First Posted

November 1, 2018

Study Start

October 8, 2018

Primary Completion

December 31, 2018

Study Completion

June 30, 2019

Last Updated

July 14, 2020

Record last verified: 2020-07

Locations