IV Iron Versus Standard Treatment for Iron Deficiency Anemia in the Emergency Department

NCT05153278 | Completed

• 1 other identifier: E18152
• Study Type: observational
• Target: 130
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will retrospectively collect data of patients infused at UMC's emergency department (ED) with long acting irons (ferric carboxymaltose, iron dextran, iron sucrose, etc.), in addition, patients infused with blood products, with intent to treat iron deficiency anemia (IDA). Patient records reviewed will be from patients who were infused at UMC ED from January 2013 to June 2018. Primary aim of analysis will be to investigate superiority between interventions implemented for treating IDA. In addition, the investigators will utilize data to characterize patients who used ED services as an avenue to receive treatment for IDA. Further, the investigators will conduct cost analysis between different IDA directed treatments administered in the ED at UMC.

Conditions

Iron Deficiency Anemia Treatment; Iron-deficiency; Iron Deficiency Anemia Due to Blood Loss; Iron Deficiency Anemia

Keywords

iron deficiency anemia

Outcome Measures

Primary Outcomes (1)

• Change in hemoglobin

  Change in serum hemoglobin over time

  180 days

Secondary Outcomes (1)

• Change in MCV (mean corpuscular volume)

  180 days

Study Arms (2)

Control group

Patients that received standard treatment (packed red blood cells) for iron deficiency anemia

Biological: Packed red blood cells

Experimental group

Patients that received intravenous iron instead of standard treatment (packed red blood cells) for iron deficiency anemia

Drug: Intravenous drug

Interventions

Packed red blood cells BIOLOGICAL

Standard treatment for iron deficiency anemia (control)

Also known as: PRBC

Control group

Intravenous drug DRUG

Experimental treatment for iron deficiency treatment

Also known as: Intravenous iron

Experimental group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with iron deficiency anemia treated with intravenous iron or packed red blood cells

You may qualify if:

• Patients receiving one IDA intervention in the UMC ED who had at least one complete blood count or hemoglobin after discharge from the emergency department or hospital

You may not qualify if:

• Patients with no records of follow up

Sponsors & Collaborators

• Texas Tech University Health Sciences Center, El Paso: lead

Study Sites (1)

Texas Tech University Health Sciences Center El Paso

El Paso, Texas, 79905, United States

Location

MeSH Terms

Conditions

Anemia, Iron-Deficiency

Interventions

Infusion Pumps

Condition Hierarchy (Ancestors)

Anemia, Hypochromic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Iron Deficiencies; Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Equipment and Supplies; Artificial Organs; Surgical Equipment

Study Officials

• Gregory Patek, MD

  Texas Tech University Health Sciences Center, El Paso

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 29, 2021
• First Posted: December 10, 2021
• Study Start: October 26, 2018
• Primary Completion: August 26, 2020
• Study Completion: August 26, 2020
• Last Updated: March 24, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)