Graded Motor Imagery and Total Knee Arthroplasty

NCT05138406 | Unknown

• 1 other identifier: 2021/173
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

This study was planned to investigate the long-term effectiveness of the early application of graded motor imagery therapy on pain parameters, functional performance, motor imagery skill, and kinesiophobia in individuals who underwent total knee arthroplasty surgery after knee osteoarthritis.

Conditions

Total Knee Arthroplasty

Keywords

Graded Motor Imagery; Pain; Rehabilitation; Total knee arthroplasty

Outcome Measures

Primary Outcomes (6)

• Pain intensity

  Pain at rest and during activity will be evaluated with the help of the Visual Analogue Scale (VAS). The VAS is a 10 cm scale that rates 0 points as "no pain" and 10 points as "worst pain imaginable".

  Baseline

• Pain intensity

  Pain at rest and during activity will be evaluated with the help of the Visual Analogue Scale (VAS). The VAS is a 10 cm scale that rates 0 points as "no pain" and 10 points as "worst pain imaginable".

  6 weeks after surgery

• Pain intensity

  Pain at rest and during activity will be evaluated with the help of the Visual Analogue Scale (VAS). The VAS is a 10 cm scale that rates 0 points as "no pain" and 10 points as "worst pain imaginable".

  6 months after surgery

• WOMAC

  Functional status will be assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). It consists of three subgroups as pain (5 items), stiffness (2 items) and physical function (17 items) and a total of 24 items. Each item has an evaluation score of 0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe.

  Baseline

• WOMAC

  Functional status will be assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). It consists of three subgroups as pain (5 items), stiffness (2 items) and physical function (17 items) and a total of 24 items. Each item has an evaluation score of 0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe.

  6 weeks after surgery

• WOMAC

  Functional status will be assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). It consists of three subgroups as pain (5 items), stiffness (2 items) and physical function (17 items) and a total of 24 items. Each item has an evaluation score of 0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe.

  6 months after surgery

Secondary Outcomes (30)

• Pressure pain threshold

  Baseline

• Pressure pain threshold

  6 weeks after surgery

• Pressure pain threshold

  6 months after surgery

• Central sensitization

  Baseline

• Central sensitization

  6 weeks after surgery

Study Arms (2)

Graded Motor Imagery

EXPERIMENTAL

Individuals will receive standard rehabilitation and graded motor imagery treatment.

Other: Graded Motor Imagery; Other: Standard Rehabilitation

Standard Rehabilitation Group

ACTIVE COMPARATOR

Standard rehabilitation will be applied.

Other: Standard Rehabilitation

Interventions

Graded Motor Imagery OTHER

The graded motor imaging program will be set to 2 weeks each component. Participants will receive lateralization for the first 2 weeks, motor imagery for 2 weeks, and mirror therapy for 2 weeks. At the same time, standard rehabilitation will be applied for 6 weeks. Treatments will begin 24-48 hours after surgery. Treatments will be applied under the control of a physiotherapist 3 days a week and as home exercise 3 days a week.

Graded Motor Imagery

Standard Rehabilitation OTHER

Standard rehabilitation consisting of cold therapy, stretching and strengthening exercises will be applied. Treatment will be applied under the control of a physiotherapist 3 days a week and as home exercise 3 days a week.

Graded Motor Imagery; Standard Rehabilitation Group

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with knee osteoarthritis and being on the waiting list to receive unilateral total knee arthroplasty
• Approved by the orthopedist for early physiotherapy treatment after total knee arthroplasty

You may not qualify if:

• \- Individuals undergoing revision total knee arthroplasty or undergoing bilateral total knee arthroplasty,
• Contralateral knee osteoarthritis (defined by activity greater than 4/10 pain)
• Having undergone any physical therapy intervention or other surgery in the last 6 months
• Any neurological, cardiac, pulmonary or psychiatric disease (eg, uncontrolled diabetes mellitus, neoplasms, uncontrolled blood pressure, neurological conditions) before or after surgery;
• Fracture, infection in the acute postoperative phase or presence of fever
• Cognitive impairments that alter the probability of correct understanding of the motor imagery program
• Body mass index \> 35 kg / m2
• Difficulties with understanding or communication
• Insufficient knowledge of Turkish to follow the study instructions.

Sponsors & Collaborators

• Inonu University: lead

Study Sites (1)

Inonu Unıversity

Malatya, Turkey (Türkiye)

RECRUITING

Related Publications (4)

• La Touche R, Grande-Alonso M, Cuenca-Martinez F, Gonzalez-Ferrero L, Suso-Marti L, Paris-Alemany A. Diminished Kinesthetic and Visual Motor Imagery Ability in Adults With Chronic Low Back Pain. PM R. 2019 Mar;11(3):227-235. doi: 10.1016/j.pmrj.2018.05.025. Epub 2019 Jan 15.

  PMID: 29908933 BACKGROUND

• Dilek B, Ayhan C, Yagci G, Yakut Y. Effectiveness of the graded motor imagery to improve hand function in patients with distal radius fracture: A randomized controlled trial. J Hand Ther. 2018 Jan-Mar;31(1):2-9.e1. doi: 10.1016/j.jht.2017.09.004. Epub 2017 Nov 6.

  PMID: 29122370 BACKGROUND

• Gurudut P, Jaiswal R. Comparative Effect of Graded Motor Imagery and Progressive Muscle Relaxation on Mobility and Function in Patients with Knee Osteoarthritis: A Pilot Study. Altern Ther Health Med. 2022 Mar;28(3):42-47.

  PMID: 33128533 BACKGROUND

• Lee HG, An J, Lee BH. The Effect of Progressive Dynamic Balance Training on Physical Function, The Ability to Balance and Quality of Life Among Elderly Women Who Underwent a Total Knee Arthroplasty: A Double-Blind Randomized Control Trial. Int J Environ Res Public Health. 2021 Mar 3;18(5):2513. doi: 10.3390/ijerph18052513.

  PMID: 33802559 BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Burcu TALU

  Inonu University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Busra CANDIRI

CONTACT

+905073780717; candiri_17@hotmail.com

Burcu TALU

CONTACT

+905317910984; fzt.burcu@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: October 28, 2021
• First Posted: December 1, 2021
• Study Start: February 28, 2022
• Primary Completion: April 1, 2023
• Study Completion: June 1, 2023
• Last Updated: November 14, 2022

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)