Quality of Life and Function of Patients With Pelvic Tumors After Undergoing Hemipelvectomy

NCT05134142 | Recruiting

• 2 other identifiers: PA12-1046NCI-2021-11297
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to determine the functional outcomes of patients who underwent internal hemipelvectomy with or without reconstruction or external hemipelvectomy for pelvic tumors. Learning about the outcomes of these patients may help researchers determine the long-term effects of different types of hemipelvectomy procedures and may help improve quality of life.

Conditions

Malignant Primary Pelvic Neoplasm

Outcome Measures

Primary Outcomes (1)

• Functions of patients who underwent internal hemipelvectomy with or without reconstruction or have had an external hemipelvectomy

  All continuous variables including the scoring systems will be described as mean with standard deviation or median with range. Frequencies and percentages will be obtained for all categorical variables. Pediatric participants' data measures will be collected and analyzed separately from the adult populations.

  Through study completion, average of 1 year

Study Arms (1)

Observational (Physical tests, questionnaires, record review)

Patients undergo physical performance assessments and complete quality of life assessments and questionnaires pre-hemipelvectomy, at 6 weeks post-hemipelvectomy, and then every 3 months up to 12 months and yearly thereafter for 10 years. Patients who are 1 year out from surgery complete pain-related questionnaires once. Patients who have already undergone hemipelvectomy prior to enrollment undergo medical record review.

Other: Electronic Health Record Review; Other: Physical Performance Testing; Other: Quality-of-Life Assessment; Other: Questionnaire Administration

Interventions

Electronic Health Record Review OTHER

Undergo medical record review

Observational (Physical tests, questionnaires, record review)

Physical Performance Testing OTHER

Undergo physical performance testing

Also known as: Physical Fitness Testing, Physical Function Testing

Observational (Physical tests, questionnaires, record review)

Quality-of-Life Assessment OTHER

Complete assessments

Also known as: Quality of Life Assessment

Observational (Physical tests, questionnaires, record review)

Questionnaire Administration OTHER

Complete questionnaire

Observational (Physical tests, questionnaires, record review)

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients within the institution who have undergone or will undergo a hemipelvectomy.

You may qualify if:

• Patients within the institution who have undergone or will undergo a hemipelvectomy

You may not qualify if:

• \- None

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• M D Anderson Cancer Center website

MeSH Terms

Interventions

Exercise Test

Intervention Hierarchy (Ancestors)

Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Ergometry; Investigative Techniques

Study Officials

• Valerae O Lewis

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Valerae O Lewis

CONTACT

713-792-5073; volewis@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 11, 2021
• First Posted: November 24, 2021
• Study Start: March 27, 2013
• Primary Completion (Estimated): April 30, 2027
• Study Completion (Estimated): April 30, 2027
• Last Updated: May 20, 2026

Record last verified: 2026-05

Locations

US (1)