NCT05126589

Brief Summary

The study aims to characterize the distributive pattern of viruses in upper airway and its relationship with influenza seasons, symptomatology and exposure setting. A total of 500 adults residing in Hong Kong would be recruited, who would complete a questionnaire and return self-collected nasal and throat swabs for metagenomic analyses.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
8mo left

Started Dec 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress87%
Dec 2021Jan 2027

First Submitted

Initial submission to the registry

November 17, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 19, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

December 28, 2021

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2027

Last Updated

January 24, 2025

Status Verified

January 1, 2025

Enrollment Period

4.5 years

First QC Date

November 17, 2021

Last Update Submit

January 22, 2025

Conditions

COVID-19 Respiratory Infection

Keywords

metagenomicrespiratory virus infectionsexposure risk

Outcome Measures

Primary Outcomes (1)

  • Positive identification of viruses

    Proportion of specimens with identified respiratory virus taxa

    4 years

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects would be invited by post through randomly selected households throughout the territory of Hong Kong.

You may qualify if:

  • adults normally residing in Hong Kong
  • could communicate in English and/or Chinese
  • provision of consent

You may not qualify if:

  • individuals with mental illness
  • prisoners

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Prince of Wales Hospital

Hong Kong, Hong Kong, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

nasal and throat swabs

Study Officials

  • Shui Shan Lee

    Chinese University of Hong Kong

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shui Shan Lee, MD

CONTACT

85222528812sslee@cuhk.edu.hk

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Professor

Study Record Dates

First Submitted

November 17, 2021

First Posted

November 19, 2021

Study Start

December 28, 2021

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

January 1, 2027

Last Updated

January 24, 2025

Record last verified: 2025-01

Locations

CN(1)