Emergency Department Vestibular Rehabilitation Therapy for Dizziness and Vertigo

NCT05122663 | Completed

• 1 other identifier: STU00215925
• Study Type: observational
• Target: 125
• Locations: 1 country
• Sites: 1

Brief Summary

ED-VeRT will enroll up to 125 adult emergency department (ED) patients presenting with a chief complaint of dizziness or vertigo to collect longitudinal outcomes over 3 months of follow-up. This will include 50 patients who were evaluated by an ED physical therapist (ie, vestibular rehabilitation) during their ED visit and 50 patients who received usual care. The aims of this trial are to: (1) obtain initial estimates of participant recruitment and retention, intra-cluster correlation, and between-group outcome differences that will inform sample size calculation for a future randomized clinical trial, and (2) assess feasibility and fidelity of a clinical classification protocol for undifferentiated dizziness among patients receiving ED vestibular rehabilitation.

Conditions

Dizziness; Vertigo

Outcome Measures

Primary Outcomes (1)

• Dizziness Handicap Inventory (DHI)

  The DHI contains 25 items quantifying self-perceived handicapping effects of dizziness symptoms.

  Three months after the index ED visit.

Secondary Outcomes (4)

• Vestibular Activities Avoidance Instrument (VAAI-9)

  Three months after the index ED visit.

• ED Diagnostic Imaging Utilization

  Index ED visit (one day)

• ED Length of Stay

  Index ED visit (up to one week)

• Patient-Reported Medication Use in Last 24 Hours

  Three months after the index ED visit.

Other Outcomes (5)

• Global Rating of Change (GROC)

  Three months after the index ED visit.

• Numeric Rating Scale (NRS)

  Three months after the index ED visit.

• Advanced Healthcare Utilization

  Three months after the index ED visit.

Study Arms (2)

ED Physical Therapy

Patients in the ED physical therapy group will have been evaluated by an emergency department physical therapist for dizziness/vertigo during their index ED visit.

Behavioral: Vestibular Rehabilitation

Usual Care

Patients in the usual care group will NOT have received an evaluation by an ED physical therapist for dizziness/vertigo symptoms during their index ED visit.

Other: Usual Care

Interventions

Vestibular Rehabilitation BEHAVIORAL

Vestibular Rehabilitation refers to the specific interventions that physical therapists provide to patients with dizziness and vertigo symptoms. These interventions can involve repositioning maneuvers, habituation exercises, gaze stabilization, and/or balance training exercises, depending on the specific etiology of dizziness and vertigo per an established clinical protocol utilizing a patient's history and exam findings. Physical therapists instruct patients in how to perform these exercises at home and provide instructions and referral for patients to follow-up with an outpatient physical therapist for further care.

ED Physical Therapy

Usual Care OTHER

Usual Care refers to any combination of diagnostic testing, medications, and patient education or counseling provided by a patient's treating ED physician.

Usual Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

ED patients presenting with a chief complaint relating to dizziness or vertigo.

You may qualify if:

• Chief complaint relating to dizziness or vertigo
• Ability to complete follow-up data collection electronically or by telephone
• English-speaking

You may not qualify if:

• Severe neurologic deficit concerning for ischemic or hemorrhagic stroke
• Known pregnancy, under police custody, unable to consent

Sponsors & Collaborators

• Northwestern University: lead

Study Sites (1)

Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States

Location

Related Publications (1)

• Kim HS, Schauer JM, Kan AK, Alinger JB, Strickland KJ, Garreau A, McCarthy DM, Taylor ZB, Fishman IL, Muschong KM, Roth HR. Emergency Department Vestibular Rehabilitation Therapy for Dizziness and Vertigo: A Nonrandomized Clinical Trial. JAMA Netw Open. 2025 Feb 3;8(2):e2459567. doi: 10.1001/jamanetworkopen.2024.59567.

  PMID: 39951266 DERIVED

MeSH Terms

Conditions

Dizziness; Vertigo

Condition Hierarchy (Ancestors)

Sensation Disorders; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Vestibular Diseases; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 12, 2021
• First Posted: November 17, 2021
• Study Start: November 16, 2021
• Primary Completion: May 1, 2023
• Study Completion: May 1, 2023
• Last Updated: July 12, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)