Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications

NCT05119829 | Unknown

• 1 other identifier: Gen_Melanoma_HeCOG
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to evaluate the genomic profiles and investigate the prevalence of germ line and pathogenic mutations in Greek population with early and metastatic melanoma and their correlation with the treatment and prognosis of the disease.

Conditions

Melanoma

Outcome Measures

Primary Outcomes (1)

• Evaluation of prevalence mutation

  Evaluation of prevalence mutation

  January 2022 to September 2022

Secondary Outcomes (1)

• ognostic significance of mutations with respect to overall survival

  January 2022 to September 2022

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with histologically confirmed melanoma skin cancer. Patients are treated in Hellenic Cooperative oncology Group affiliated departments of oncology.

You may qualify if:

• Melanoma skin cancer patients
• the ability to achieve FFPE

Sponsors & Collaborators

• Hellenic Cooperative Oncology Group: lead

Study Sites (1)

1st Dept of Medical Oncology, Metropolitan Hospital

Athens, 18547, Greece

Location

Related Publications (23)

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Biospecimen

Retention: SAMPLES WITH DNA

Formalin-Fixed-Paraffin-Embedded (FFPE) tumor tissue blocks will be collected

MeSH Terms

Conditions

Melanoma

Condition Hierarchy (Ancestors)

Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Nerve Tissue; Nevi and Melanomas; Skin Neoplasms; Neoplasms by Site; Skin Diseases; Skin and Connective Tissue Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 3, 2021
• First Posted: November 15, 2021
• Study Start: February 1, 1998
• Primary Completion: January 1, 2023
• Study Completion: December 1, 2023
• Last Updated: March 31, 2022

Record last verified: 2022-03

Locations

GR (1)