Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort

NCT05119478 | Unknown

• 1 other identifier: RECHMPL21_0612
• Study Type: observational
• Target: 594
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital. Some Gibberellin-regulated protein (GRP) in fruits and pollens have been identified as allergen, and peach GRP (peamaclein) has recently emerged as a relevant food allergen in cypress pollen-hypersensitive patients. Multiple fruit allergies might be related to cross-reactivity between GRPs. Peamaclein shares 82% identity with snakin-1 from potato. Thus, because of this hight homology the investigators want to determine the prevalence of cosensitization between these 3 allergens potato, peach and cypress.

Conditions

Allergic Rhinitis

Keywords

Cypress; gibberellin-regulated protein; peach; potato; rhinitis

Outcome Measures

Primary Outcomes (1)

• Rate of sensitization to peach and/or cypress in potato-sensitized patients

  Rate of sensitization to peach and/or cypress in potato-sensitized patients

  day 1

Secondary Outcomes (1)

• Rate of of sensitization to peach and/or cypress in potato-sensitized patients

  day 1

Eligibility Criteria

• Age: 2 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital with positive skin prick test to potato

You may qualify if:

• Patients evaluated at the Montpellier University Hospital, Allergy Unit
• children and adult with positive skin prick test to potato from february 2013 to december 2015

You may not qualify if:

• Patients under legal protection
• Patients under guardianship or under curatorship
• Patients not capable of understanding French

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

Uhmontpellier

Montpellier, 34295, France

RECRUITING

MeSH Terms

Conditions

Rhinitis, Allergic; Rhinitis

Condition Hierarchy (Ancestors)

Nose Diseases; Respiratory Tract Diseases; Respiratory Hypersensitivity; Otorhinolaryngologic Diseases; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Respiratory Tract Infections; Infections

Study Officials

• Davide CAIMMI

  University Hospital, Montpellier

  STUDY DIRECTOR

Central Study Contacts

Davide CAIMMI, MD

CONTACT

467336112; davide.caimmi@gmail.com

Evangéline CLARK, doctor

CONTACT

467336107; e-clark@chu-montpellier.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 27, 2021
• First Posted: November 15, 2021
• Study Start: October 1, 2021
• Primary Completion: January 1, 2022
• Study Completion: April 1, 2022
• Last Updated: November 15, 2021

Record last verified: 2021-10

Locations

FR (1)