Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan

NCT05107401 | Completed Results

• 2 other identifiers: AAAT7871R21TW012017
• Study Type: interventional
• Target: 216
• Locations: 1 country
• Sites: 1

Brief Summary

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). NIH has emphasized the need for research on interventions to reduce HIV-associated stigma and its impact on the prevention and treatment of HIV/AIDS, particularly in low and middle income countries (LMICs). The proposed study has the highest public health significance: it uses a community-based participatory approach to engage local AYA to develop a digital crowdsourced HIV stigma reduction and self-testing intervention to reduce HIV stigma and increase HIV testing. Study Aim 1: To develop a crowdsourced digital HIV stigma reduction and self-testing intervention targeting AYA in Kazakhstan. Using a community-based participatory approach that engages local adolescents and young adults (AYA) and youth organizations, we will launch a national crowdsourcing contest in which AYA will design multimedia content to reduce HIV stigma in order to promote HIV testing among peers. Study Aim 2: To pilot test this crowdsourced HIV stigma reduction and self-testing intervention in a preliminary efficacy trial. We will assess the intervention's feasibility and acceptability and obtain preliminary estimates of its effects on decreasing HIV stigma (primary outcome) and increasing HIV testing (secondary outcome) among AYA in Kazakhstan who received the intervention compared to individuals who did not. Participants (n=168) will be randomized 1:1 to: 1) receive the winning multimedia crowdsourced HIV stigma reduction content and a link for HIV self-testing, or 2) receive standard Kazakhstan Ministry of Health HIV informational materials and a link for HIV self-testing.

Conditions

Stigma, Social; HIV Testing

Keywords

HIV stigma

Outcome Measures

Primary Outcomes (1)

• Mean Score Change in Total HIV Stigma Scale

  The scale/questionnaire is comprised of 17 items on a 5-point Likert scale (score range from 17-85). Higher scores indicate higher levels of stigma. Outcome will be assessed in mean score change from baseline to 3 months follow-up.

  Baseline and 3 months

Secondary Outcomes (5)

• Mean Change in Perceived HIV Test Stigma

  Baseline and 3 months

• Mean Change in Perceived HIV Healthcare Stigma Subscale

  Baseline and 3 months

• Mean Change in Fear & Judgement HIV Stigma Sub-scale

  Baseline and 3 months

• Mean Change in Perceived Community HIV Stigma Subscale

  Baseline and 3 months

• Uptake of HIV Self-test

  After baseline and by the 3 month follow-up period

Study Arms (2)

Crowdsourced Intervention

EXPERIMENTAL

The digital crowdsourced intervention will be presented to participants in the intervention arm.

Behavioral: Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults

Standard of Care

NO INTERVENTION

Standard HIV informational materials currently used by the Kazakhstan Ministry of Health will be presented to participants in the control arm.

Interventions

Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults BEHAVIORAL

Adolescents and young adults will participate in a crowdsourcing contest to create digital materials to reduce HIV stigma in order to increase HIV testing. Entries will be judged by a community judging panel and expert judging panel. Winning entries will be selected for the digital intervention and presented to participants in the intervention arm.

Crowdsourced Intervention

Eligibility Criteria

• Age: 16 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Age 16-24
• Report previous sex with another individual
• Reside in Kazakhstan

You may not qualify if:

• Not willing to provide consent or not able to understand study procedures

Sponsors & Collaborators

• Columbia University: lead
• National Institutes of Health (NIH): collaborator
• Fogarty International Center of the National Institute of Health: collaborator
• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): collaborator

Study Sites (1)

Columbia University Global Health Research Center of Central Asia

Almaty, 050040, Kazakhstan

Location

MeSH Terms

Conditions

Social Stigma

Condition Hierarchy (Ancestors)

Social Behavior; Behavior

Results Point of Contact

• Title: Dr. Alissa Davis
• Organization: Columbia University

ad3324@columbia.edu

212-851-2224

Study Officials

• Alissa Davis, PhD

  Columbia University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Social Work, School of Social Work

Model Details: Participants will be randomized to receive the digital crowdsourced intervention or standard of care (existing HIV informational materials). We will examine effects of the intervention on reducing HIV stigma and increasing HIV testing.

Study Record Dates

• First Submitted: October 25, 2021
• First Posted: November 4, 2021
• Study Start: January 24, 2023
• Primary Completion: August 22, 2023
• Study Completion: August 22, 2023
• Last Updated: December 17, 2024
• Results First Posted: December 17, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Data will become available to outside investigators after the study investigative team has cleaned and analyzed the data and written their proposed papers.
• Access Criteria: Have a proposed plan for data analysis Completed human subjects training Obtained Institutional Review Board approval to access and analyze the data

Locations

KA (1)