NCT05615935

Brief Summary

This is a randomized controlled trial design. The investigators plan to recruit about 60 to 70 emergency department nurses from a medical center in Taipei, Taiwan. After completing the paper consent form, these nurses will be randomly assigned to 2 groups, which are a control group and an experimental group. The pre-test includes the demographic data sheet, HIV testing related knowledge and practice scale, and The Health Care Provider HIV/ AIDS Stigma Scale (HPASS). All nurses will receive a learning material when they finish the pre-test. In addition, the experimental group will be provided a real HIV testing and counselling by a researcher. The post-test will be finished one month later of pre-test in the control group, and one month later while the intervention completed in the experimental group. The semi-structural interview will be performed to the experimental group to collect and analyze their opinion toward the experiential HIV testing.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
74

participants targeted

Target at P25-P50 for not_applicable hiv

Timeline
Completed

Started Nov 2022

Shorter than P25 for not_applicable hiv

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 31, 2022

Completed
9 days until next milestone

Study Start

First participant enrolled

November 9, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 14, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2023

Completed
22 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 23, 2023

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

August 2, 2024

Completed
Last Updated

October 1, 2025

Status Verified

September 1, 2025

Enrollment Period

3 months

First QC Date

October 31, 2022

Results QC Date

May 22, 2023

Last Update Submit

September 11, 2025

Conditions

Keywords

stigmaknowledgeEducation, nursingsituated learning

Outcome Measures

Primary Outcomes (2)

  • HIV Testing Related Knowledge and Practice

    A self-development scale, known as the "HIV Testing-Related Knowledge and Practice Scale," is employed to assess individuals' knowledge and practices pertaining to HIV testing. The scale consists of twenty-eight questions, encompassing both True-False and multiple-choice formats. Participants earn one point for each correct answer, contributing to a total score that ranges from the minimum scores of 0 to the maximum scores of 28. Higher scores signify a more positive outcome, indicating enhanced HIV testing-related knowledge and practice among the participants.

    pre-test(Baseline) and post-test (week 4)

  • HIV Related Stigma

    The Healthcare Provider HIV/AIDS Stigma Scale (HPASS) will be used to assess this outcome. The instrument contains 30 items, each scored on a six-point Likert scale, yielding a minimum total score of 30 and a maximum of 180. Higher scores reflect greater levels of stigma toward people living with HIV, indicating a worse outcome. Validation of the HPASS through factor analysis identified three underlying dimensions. The stereotyping dimension (11 items; score range: 11-66) reflects negative cognitions and beliefs about people living with HIV. The prejudice dimension (13 items; score range: 13-78) captures emotionally driven attitudes. The discrimination dimension (6 items; score range: 6-36) represents behavioral responses stemming from negative attitudes. For all dimensions, higher scores indicate worse outcomes. These 3 dimensions(as sub-scale scores) for stereotyping, prejudice, and discrimination will also be calculated and analyzed.

    pre-test (Baseline) and post-test (Week 4)

Study Arms (2)

Get a learning material and a experiential HIV Testing

EXPERIMENTAL

These participants in the experimental group will be provided a learning material about HIV testing, then an experiential HIV Testing, which includes HIV testing and counselling, education and discussion, and a post-test interviews will be provided.

Other: Experiential HIV Testing

Get a learning material only

NO INTERVENTION

These participants in the control group will be provided a learning material about HIV testing only. After the post-test, the experiential HIV Testing will be provided to them.

Interventions

The content of experiential HIV Testing includes HIV testing, counselling, and education and discussion.

Get a learning material and a experiential HIV Testing

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- have registered nurse license and do clinical care in emergency department

You may not qualify if:

  • have registered nurse license but doesn't do clinical care, likes head nurse.
  • do clinical care in emergency department but doesn't have registered nurse license, like volunteers or assistant nurse.
  • have experienced non-occupational HIV testing.
  • had been a nurse in HIV/AIDS-focus ward or HIV/AIDS case manager.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Nursing of National Taiwan University

Taipei, 100, Taiwan

Location

Related Publications (1)

  • He CR, Chang JC, Liu CY, Yang BJ, Hung YH, Chiou PY. Enhancing HIV knowledge and reducing stigma among emergency nurses through experiential self-testing: A mixed-methods study. Nurse Educ Pract. 2025 Dec 18;91:104694. doi: 10.1016/j.nepr.2025.104694. Online ahead of print.

MeSH Terms

Conditions

Acquired Immunodeficiency SyndromeSocial Stigma

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesSocial BehaviorBehavior

Results Point of Contact

Title
Dr. Piao-Yi Chiou
Organization
National Taiwan University

Study Officials

  • CHENG-RU HE, Bachelor

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 31, 2022

First Posted

November 14, 2022

Study Start

November 9, 2022

Primary Completion

February 1, 2023

Study Completion

February 23, 2023

Last Updated

October 1, 2025

Results First Posted

August 2, 2024

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations