NCT05102318

Brief Summary

The aim of the present study is to evaluate Mineral Trioxide Aggregate and Biodentine in direct pulp capping, partial pulpotomy, and pulpotomy in primary molars.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2020

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

October 20, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

November 1, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2022

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2022

Completed
Last Updated

February 11, 2022

Status Verified

January 1, 2022

Enrollment Period

2 years

First QC Date

October 20, 2021

Last Update Submit

January 28, 2022

Conditions

Keywords

Direct pulp capping, Partial Pulpotomy, and Pulpotomy

Outcome Measures

Primary Outcomes (1)

  • Is to evaluate the clinical and radiographic success rates of Mineral Trioxide Aggregate and Biodentine in direct pulp capping, partial pulpotomy, and pulpotomy in primary molars.

    Is to evaluate the clinical and radiographic success rates of Mineral Trioxide Aggregate and Biodentine in direct pulp capping, partial pulpotomy, and pulpotomy in primary molars.

    18 months

Study Arms (6)

Direct Pulp Capping with Biodentine

EXPERIMENTAL

Direct Pulp Capping with Biodentine

Procedure: Direct Pulp Capping

Partial Pulpotomy with Biodentine

EXPERIMENTAL

Partial Pulpotomy with Biodentine

Procedure: Partial Pulpotomy

Pulpotomy with Biodentine

EXPERIMENTAL

Pulpotomy with Biodentine

Procedure: Pulpotomy

Direct Pulp Capping with MTA

EXPERIMENTAL

Direct Pulp Capping with MTA

Procedure: Direct Pulp Capping

Partial Pulpotomy with MTA

EXPERIMENTAL

Partial Pulpotomy with MTA

Procedure: Partial Pulpotomy

Pulpotomy with MTA

EXPERIMENTAL

Pulpotomy with MTA

Procedure: Pulpotomy

Interventions

Direct Pulp Capping

Direct Pulp Capping with BiodentineDirect Pulp Capping with MTA

Partial Pulpotomy

Partial Pulpotomy with BiodentinePartial Pulpotomy with MTA
PulpotomyPROCEDURE

Pulpotomy

Pulpotomy with BiodentinePulpotomy with MTA

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • No clinical symptoms or history implying irreversible pulpitis such as spontaneous pain, or pain persisting after stimuli removal.
  • Absence of periapical or interadicular radiolucencies, inflammatory root resorption, sinus tract or gingival abscess.

You may not qualify if:

  • Children who are extremely uncooperative and difficult to manage.
  • Children suffering from any physically or mentally disability that will complicate the treatment: Special Health Care needs (SHCN).
  • Teeth of poor prognosis due to presence of an abscess or a sinus, mobility, advanced bone or root resorption or Non-Restorable teeth.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ain Shams University

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Dental Pulp Diseases

Interventions

Pulpotomy

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

EndodonticsDentistry

Study Officials

  • Noha Kabil, Professor

    British University In Egypt

    STUDY DIRECTOR

Central Study Contacts

Nadia Metwalli, Professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

October 20, 2021

First Posted

November 1, 2021

Study Start

April 1, 2020

Primary Completion

April 1, 2022

Study Completion

September 1, 2022

Last Updated

February 11, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations