NCT05101434

Brief Summary

Periodontitis and gingivitis are one of the most infectious diseases in humans. Several studies have been carried out on the dependence of periodontitis and stroke. The aim of this study was to investigate gingivitis and periodontitis as risk factors for stroke in the Pakistani population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 10, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 10, 2021

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2021

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 18, 2021

Completed
14 days until next milestone

First Posted

Study publicly available on registry

November 1, 2021

Completed
Last Updated

November 1, 2021

Status Verified

October 1, 2021

Enrollment Period

6 months

First QC Date

October 18, 2021

Last Update Submit

October 29, 2021

Conditions

GingivitisPeriodontitisStroke

Outcome Measures

Primary Outcomes (2)

  • Gingivitis

    Measurement of bleeding site while probing and this was done with gingival index

    baseline

  • Periodonitis

    Measurement of periodontal pockets while probing and this was done with community periodontal idex

    baseline

Interventions

Periodontal ProbingDIAGNOSTIC_TEST

with the help Michigan probe, periodontal pocket measurement was done.

Also known as: ROAG revised oral assessment guide, Community periodontal index, Gingival Index

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All the patients with stroke (both ischemic and hemorrhagic)

You may qualify if:

  • Diagnosed stroke by using brain imaging from magnetic resonance imaging and/or computerized tomography.

You may not qualify if:

  • Not willing to participate
  • Neurological complications other than stroke

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shaheed Zulfiqar Ali Bhutto Medical University

Islamabad, Capital, 44000, Pakistan

Location

MeSH Terms

Conditions

GingivitisPeriodontitisStroke

Condition Hierarchy (Ancestors)

InfectionsGingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Muhammad Hassan, MD

    Shaheed Zulfiqar Ali Bhutto Medical University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Registrar Neurology

Study Record Dates

First Submitted

October 18, 2021

First Posted

November 1, 2021

Study Start

January 10, 2021

Primary Completion

July 10, 2021

Study Completion

July 20, 2021

Last Updated

November 1, 2021

Record last verified: 2021-10

Locations

PA(1)