Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia

NCT05101408 | Completed

• 1 other identifier: RECHMPL21_0597
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature. If speech-language therapy (SLT) has been shown to be effective for persons with aphasia, the relative efficiency of one SLT strategy over another remains a matter of debate. The influential relationship between language, executive functions and aphasia rehabilitation outcomes has been addressed in a number of studies, but only few of them have studied the effect of adding an executive training to linguistic therapies.The aim of this study is to measure the efficiency of a protocol combining anomia therapy and executive training on naming skills and discourse in post-stroke aphasic persons at the chronic stage

Conditions

Anomia; Post-stroke Aphasia

Keywords

Aphasia; Speech-Language Therapy; Anomia; Executive functions

Outcome Measures

Primary Outcomes (2)

• Evolution of individual naming scores

  Evolution of individual naming scores during baseline and treatment phases Participants are asked to name pictures from a personal naming task constituted of 100 black and white pictures and scores are expressed as percent of correct responses (min 0, max 100): higher percents meaning a better outcome. A visual analysis of the evolution of these scores along the course of the treatment will be conducted.

  2 days

• Comparison of discourse

  Comparison of discourse scores before and after the treatment For each participant, four different samples of discourse are elicited before and after the treatment (picture description, personal narrative, book supported narrative, procedural information). The mean number of correct words per minute is then computed for each participant, and compared between the two time points, higher scores meaning a better outcome.

  2 days

Secondary Outcomes (1)

• Comparison of executive scores

  2 days

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Person with post-stroke aphasia at the chronic stage, receiving SLT rehabilitation

You may qualify if:

• \< age \> 80 years
• adult person with chronic post-stroke aphasia (\> 6 months postonset)
• receiving SLT rehabilitation 3 times a Week

You may not qualify if:

• presence of apraxia of speech
• major impairment of comprehension
• history of other neurological or psychiatric disease
• presence of apraxia of speech
• presence of major impairment of comprehension
• presence of history of other neurological or psychiatric disease

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

Uhmontpellier

Montpellier, 34295, France

Location

MeSH Terms

Conditions

Anomia; Aphasia; Communication Disorders

Condition Hierarchy (Ancestors)

Language Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Speech Disorders; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Sylvie Moritz-Gasser

  University Hospital, Montpellier

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 19, 2021
• First Posted: November 1, 2021
• Study Start: September 1, 2021
• Primary Completion: December 1, 2021
• Study Completion: December 30, 2021
• Last Updated: April 12, 2022

Record last verified: 2022-04

Locations

FR (1)