Effect of Phosphate Exposure on Workers Health

NCT05094076 | Unknown

• 1 other identifier: Phosphate exposure
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

To minimize negative health effects on health of workers in phosphate mining, it is important to assess, and diagnose health related effect of phosphate exposure \& health hazards related to miners. Early reporting, diagnosis, and intervention can limit the severity of health hazards, improve the health services. To our knowledge no local previous studies were done in this area.

Conditions

Work-related Illness

Outcome Measures

Primary Outcomes (1)

• pneumoconiosis or not

  The chest radiographs obtained will be classified according to the International Labor Organization (ILO) System for Classification of Radiographs for Pneumoconiosis \[ILO, 1980\]. Film quality, profusion, and shape and size of opacities will be evaluated by this method. Radiographic evidence of silicosis was defined as a profusion score of 1/0 or greater

  through study completion, an average of 1 year

Secondary Outcomes (1)

• dental caries

  through study completion, an average of 1 year

Interventions

chest x ray RADIATION

The chest radiographs obtained will be classified according to the International Labor Organization (ILO) System for Classification of Radiographs for Pneumoconiosis \[ILO, 1980\]. Film quality, profusion, and shape and size of opacities will be evaluated by this method. Radiographic evidence of silicosis was defined as a profusion score of 1/0 or greater

Also known as: spirometer

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Active working miners working in phosphate mines with minimum exposure 5 year.

You may qualify if:

• Active working miners working in phosphate mines with minimum exposure 5 year.
• Had free pre-employment records.

You may not qualify if:

• Workers don't record phosphate exposure as in administration department.
• Workers with less than 5-year exposure
• Workers known to had autoimmune disorder before joining job.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Stewart AG. Mining is bad for health: a voyage of discovery. Environ Geochem Health. 2020 Apr;42(4):1153-1165. doi: 10.1007/s10653-019-00367-7. Epub 2019 Jul 9.

  PMID: 31289975 BACKGROUND

• Khelifi M, Zarrouk A, Nury T, Hamed H, Saguem S, Salah RB, Riedinger JM, Lizard G. Cytokine and eicosanoid profiles of phosphate mine workers. J Toxicol Sci. 2014 Jun;39(3):465-74. doi: 10.2131/jts.39.465.

  PMID: 24849681 BACKGROUND

• Kalliny MS, Bassyouni MI. Immune response due to silica exposure in Egyptian phosphate mines. J Health Care Poor Underserved. 2011;22(4 Suppl):91-109. doi: 10.1353/hpu.2011.0156.

  PMID: 22102308 BACKGROUND

• Amin WM, Al-Omoush SA, Hattab FN. Oral health status of workers exposed to acid fumes in phosphate and battery industries in Jordan. Int Dent J. 2001 Jun;51(3):169-74. doi: 10.1002/j.1875-595x.2001.tb00835.x.

  PMID: 11563682 BACKGROUND

MeSH Terms

Interventions

X-Rays

Intervention Hierarchy (Ancestors)

Electromagnetic Radiation; Electromagnetic Phenomena; Magnetic Phenomena; Physical Phenomena; Radiation; Radiation, Ionizing

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle investigator

Study Record Dates

• First Submitted: September 28, 2021
• First Posted: October 26, 2021
• Study Start: January 1, 2022
• Primary Completion: January 30, 2023
• Study Completion: December 30, 2023
• Last Updated: October 26, 2021

Record last verified: 2021-09