Prediabetes and Newly Diagnosed Diabetes in Chronic Heart Failure
Prevalence of Prediabetes and Newly Diagnosed Diabetes in Patients With HFpEF( Heart Failure With Preserved Ejection Fraction) and HFrEF(Heart Failure With Reduced Ejection Fraction) in Sohag University Hospital
1 other identifier
observational
100
0 countries
N/A
Brief Summary
The aim the study is to determine the prevalence of prediabetic dysglycemia and newly diagnosed diabetes among individuals with CHF(chronic heart failure) in sohag university hospital patients .
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2022
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 13, 2021
CompletedFirst Posted
Study publicly available on registry
October 22, 2021
CompletedStudy Start
First participant enrolled
December 30, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
January 30, 2023
CompletedJanuary 3, 2023
December 1, 2022
Same day
September 13, 2021
December 30, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Heart failure hospitalization.
Heart failure hospitalization or cardiovascular (CV) death, and all-cause death, and estimated hazard ratios (HR) by use of multivariable Cox regression models.
From date of randomization up to 1 month
Study Arms (3)
HFrEF " Heart failure with reduced ejection fraction"
chronic heart failure with echocardiographic finding of LVEF "Left ventricular ejection fraction" equal or less than 40%
HFmrEF "Heart failure with mildly reduced ejection fraction"
chronic heart failure with echocardiographic finding of LVEF between 41% and 49%
HFpEF " Heart failure with preserved ejection fraction"
chronic heart failure with echocardiographic finding of LVEF equal or more than 50%
Interventions
hbA1C will be measured for all patients and results will be analysed into Non diabetic, Prediabetic and Diabetic
Eligibility Criteria
All patients presented by heart failure NYHA class 2 or more and admitted to Sohag University hospital according to inclusion and exclusion criterea
You may qualify if:
- All patients presented by heart failure
- years or older
- Classified according to NYHA " New York Heart Association" classification from NYHA class 2 and more
You may not qualify if:
- Overt diabetes
- Rheumatic Heart Disease
- Congenital heart disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Related Publications (1)
Nielsen R, Jorsal A, Iversen P, Tolbod L, Bouchelouche K, Sorensen J, Harms HJ, Flyvbjerg A, Botker HE, Wiggers H. Heart failure patients with prediabetes and newly diagnosed diabetes display abnormalities in myocardial metabolism. J Nucl Cardiol. 2018 Feb;25(1):169-176. doi: 10.1007/s12350-016-0622-0. Epub 2016 Jul 29.
PMID: 27473218BACKGROUND
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 6 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
September 13, 2021
First Posted
October 22, 2021
Study Start
December 30, 2022
Primary Completion
December 30, 2022
Study Completion
January 30, 2023
Last Updated
January 3, 2023
Record last verified: 2022-12