EFFECTS OF DEEP STRIPPING VERSUS KNEADING ON PAIN, RANGE OF MOTION AND FUNCTIONAL ACTIVITY AMONG INDIVIDUALS WITH KNEE OSTEOARTHRITIS

NCT05084014 | Completed

• 1 other identifier: IRB-UOL-FAHS/819-I/2021
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

This is a randomized controlled trial, 44 participants selected based on inclusion criteria from physical therapy department of Surriya Azeem Surgical Hospital, Pattoki. Participants randomly recruited into two groups, 22 in deep stripping group receiving deep stripping with conventional physical therapy and 22 in kneading group receiving kneading with conventional physical therapy. Pain, range of motion and functional mobility are the primary outcomes measured by numeric pain rating scale, universal goniometer and lower extremity functional scale. Data collected at the baseline, at the 6th session, and the 12th session.

Conditions

Knee Osteoarthritis

Keywords

Non-inflammatory disease; Degenerative joint disease; Osteoarthritis; knee joint; soft tissue mobilization; deep longitudinal stripping; kneading

Outcome Measures

Primary Outcomes (3)

• Change from the baseline in Numeric pain rating scale at 2nd and 4th week

  It is the simplest and most commonly used numeric scale in which the individual rates the pain from 0 (no pain) to 10 (worst pain) 0 = no pain, 1-3 = mild pain, 4-6 = moderate pain, 7-10 = severe pain

  Baseline, 2nd week, 4th week

• Change from baseline in Universal Goniometer at 2nd and 4th week

  the range of motion (flexion and extension) measured by using Universal Goniometer. For the range of motion, Universal Goniometer was used. It is an instrument made up of plastic material; it has a moveable arm, stationary arm and a fulcrum. The range of motion of the knee joint in extension and flexion was measured. The normal knee flexion range is 0⁰-130⁰ and the extension range is 130⁰-0⁰.

  Baseline, 2nd week, 4th week

• Change from baseline in Lower Extremity Functional Scale at 2nd and 4th week

  For functional mobility Lower Extremity Functional Scale is used. This questionnaire contains 20 questions about the ability of a person to carry out his/her daily routine tasks. Every question has 5 options 0 = Extreme difficulty or unable to perform an activity 1. = Quite a bit of difficulty 2. = Moderate difficulty 3. = a little bit of difficulty 4. = no difficulty. The participant's score was interpreted at the end by adding all the scores of 20 questions, categorizing them into very high function, moderate function, mild function and very low function

  Baseline, 2nd week, 4th week

Study Arms (2)

Deep Stripping

EXPERIMENTAL

This group will receive deep stripping technique with conventional physical therapy.

Other: Deep Stripping

Kneading

EXPERIMENTAL

This group will receive deep kneading with conventional physical therapy.

Other: Kneading

Interventions

Deep Stripping OTHER

The deep longitudinal stripping can be applied on adhesions and knots in muscles. The lengthening stokes are parallel to muscle fiber and applied in an oblique direction with the help of the thumbs of hands/ elbow/ knuckles

Deep Stripping

Kneading OTHER

kneading lifts the muscle in circular movements with the help of the hands. It lifted, rolled, and squeezed muscle

Kneading

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Chronic osteoarthritis (more than 3 months) with pain in one knee joint (unilateral)
• A prior medical diagnosis having radiographic evidence of grade 2 and 3 of Kellgren and Lawrence criteria for knee osteoarthritis by an orthopedic.
• Pain intensity level more than 3 points of the numeric pain rating scale.

You may not qualify if:

• Any acute inflammation, contracture, or surgery affecting the knee joint.
• Any cognitive problem.
• Participants taking non-steroid anti-inflammatory drugs, intra-articular injection, or physical therapy within the last three months for the knee joint.
• Participants having a lumbar spine and/or any other lower limb impairment and/or surgery affecting knee joint.

Sponsors & Collaborators

• University of Lahore: lead

Study Sites (1)

M.Mubeen Javed

Pattoki, Punjab Province, 55300, Pakistan

Location

Related Publications (6)

• GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-1858. doi: 10.1016/S0140-6736(18)32279-7. Epub 2018 Nov 8.

  PMID: 30496104 BACKGROUND

• Peters AE, Akhtar R, Comerford EJ, Bates KT. The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint. Sci Rep. 2018 Apr 12;8(1):5931. doi: 10.1038/s41598-018-24258-6.

  PMID: 29651151 BACKGROUND

• Ilas DC, Churchman SM, McGonagle D, Jones E. Targeting subchondral bone mesenchymal stem cell activities for intrinsic joint repair in osteoarthritis. Future Sci OA. 2017 Sep 6;3(4):FSO228. doi: 10.4155/fsoa-2017-0055. eCollection 2017 Nov.

  PMID: 29134116 BACKGROUND

• Karaborklu Argut S, Celik D, Kilicoglu OI. The Combination of Exercise and Manual Therapy Versus Exercise Alone in Total Knee Arthroplasty Rehabilitation: A Randomized Controlled Clinical Trial. PM R. 2021 Oct;13(10):1069-1078. doi: 10.1002/pmrj.12542. Epub 2021 Feb 3.

  PMID: 33352007 BACKGROUND

• Ferreira RM, Torres RT, Duarte JA, Goncalves RS. Non-Pharmacological and Non-Surgical Interventions for Knee Osteoarthritis: A Systematic Review and Meta-Analysis. Acta Reumatol Port. 2019 Jul 29;44(3):173-217.

  PMID: 31356585 BACKGROUND

• Perlman A, Fogerite SG, Glass O, Bechard E, Ali A, Njike VY, Pieper C, Dmitrieva NO, Luciano A, Rosenberger L, Keever T, Milak C, Finkelstein EA, Mahon G, Campanile G, Cotter A, Katz DL. Efficacy and Safety of Massage for Osteoarthritis of the Knee: a Randomized Clinical Trial. J Gen Intern Med. 2019 Mar;34(3):379-386. doi: 10.1007/s11606-018-4763-5. Epub 2018 Dec 12.

  PMID: 30543021 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee; Joint Diseases; Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Ayesha Javed, MSPT-MSK

  University of Lahore

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: In this study, the outcome assessor will be blinded. He will just take the data regarding pain, functional mobility and measure the range of motion of the knee joint at the baseline, mid of the treatment and at the end of the treatment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: In this study there are two groups, one receiving deep longitudinal stripping technique with conventional physical therapy and the second group receiving kneading technique with conventional physical therapy

Study Record Dates

• First Submitted: October 3, 2021
• First Posted: October 19, 2021
• Study Start: February 11, 2024
• Primary Completion: October 11, 2024
• Study Completion: October 11, 2024
• Last Updated: May 20, 2025

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)