Magnetically Controlled Capsule Endoscopy in Visualization of the UGI and Small Intestine
Feasibility of the Magnetically Controlled Capsule Endoscopy in One Time Visualization of the Upper Gastrointestinal Tract and Small Intestine
1 other identifier
observational
593
1 country
1
Brief Summary
In this study, we retrospectively analyzed the videos of combined upper digestive tract and small intestine examination under MCE, so as to clarify the feasibility and diagnostic efficacy of MCE in one-time examination of the upper gastrointestinal and small intestinal mucosa.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 17, 2021
CompletedStudy Start
First participant enrolled
September 27, 2021
CompletedFirst Posted
Study publicly available on registry
October 6, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 28, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2021
CompletedOctober 6, 2021
September 1, 2021
3 months
September 17, 2021
September 28, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Success rate of UGI and small-bowel examination
The success rate of upper gastrointestinal tract and small-bowel examination under MCE is evaluated by the technical success rate, a composite outcome including the successful viewing of esophagus, stomach and duodenum, and complete small-bowel examination.
2 weeks
Secondary Outcomes (6)
Visualization of the esophagus
2 weeks
Visualization score of the gastric mucosa
2 weeks
Visualization of the small bowel
2 weeks
Examination time of esophagus, stomach, duodenum and small bowel
1 month
Detection rate of lesions
1 month
- +1 more secondary outcomes
Study Arms (1)
UGI+SB
Patients who underwent combined upper digestive tract and small intestine examination under MCE.
Interventions
Patients who underwent combined upper digestive tract and small intestine examination under MCE.
Eligibility Criteria
Patients who underwent upper gastrointestinal and small intestinal mucosal examination under MCE at Shanghai Changhai Hospital and Chinese PLA General Hospital after January 2020.
You may qualify if:
- Age ≥ 18 years old.
- Those who underwent upper gastrointestinal and small intestinal mucosal examination under magnetically controlled capsule endoscopy at Shanghai Changhai Hospital and Chinese PLA General Hospital after January 2020.
- Able to provide informed consent.
You may not qualify if:
- Patients who fail to follow the prescribed procedures for magnetically controlled capsule endoscopy;
- Patients who only undergo gastric examination under magnetically controlled capsule endoscopy;
- Patients who only undergo small bowel examination under magnetic control capsule endoscopy;
- The patient's basic information in the database is incomplete；
- Patient fail to be followed up.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Changhai Hospitallead
- Chinese PLA General Hospitalcollaborator
Study Sites (1)
Changhai Hospital
Shanghai, 200433, China
Related Publications (5)
Liao Z, Hou X, Lin-Hu EQ, Sheng JQ, Ge ZZ, Jiang B, Hou XH, Liu JY, Li Z, Huang QY, Zhao XJ, Li N, Gao YJ, Zhang Y, Zhou JQ, Wang XY, Liu J, Xie XP, Yang CM, Liu HL, Sun XT, Zou WB, Li ZS. Accuracy of Magnetically Controlled Capsule Endoscopy, Compared With Conventional Gastroscopy, in Detection of Gastric Diseases. Clin Gastroenterol Hepatol. 2016 Sep;14(9):1266-1273.e1. doi: 10.1016/j.cgh.2016.05.013. Epub 2016 May 20.
PMID: 27211503BACKGROUNDJiang X, Qian YY, Liu X, Pan J, Zou WB, Zhou W, Luo YY, Chen YZ, Li ZS, Liao Z. Impact of magnetic steering on gastric transit time of a capsule endoscopy (with video). Gastrointest Endosc. 2018 Oct;88(4):746-754. doi: 10.1016/j.gie.2018.06.031. Epub 2018 Jul 11.
PMID: 30005825BACKGROUNDLuo YY, Pan J, Chen YZ, Jiang X, Zou WB, Qian YY, Zhou W, Liu X, Li ZS, Liao Z. Magnetic Steering of Capsule Endoscopy Improves Small Bowel Capsule Endoscopy Completion Rate. Dig Dis Sci. 2019 Jul;64(7):1908-1915. doi: 10.1007/s10620-019-5479-z. Epub 2019 Feb 6.
PMID: 30725289BACKGROUNDChen X, Gao F, Zhang J. Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin. Gastroenterol Res Pract. 2018 Nov 15;2018:2524698. doi: 10.1155/2018/2524698. eCollection 2018.
PMID: 30581462BACKGROUNDLiu YW, Wang YC, Zhu JH, Jiang X, Zhou W, Zhang J, Liao Z, Linghu EQ. Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience. BMC Gastroenterol. 2022 May 4;22(1):222. doi: 10.1186/s12876-022-02302-0.
PMID: 35509022DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Zhuan Liao
Changhai Hospital,Shanghai,China
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
September 17, 2021
First Posted
October 6, 2021
Study Start
September 27, 2021
Primary Completion
December 28, 2021
Study Completion
December 30, 2021
Last Updated
October 6, 2021
Record last verified: 2021-09
Data Sharing
- IPD Sharing
- Will not share