Effect of Exercise on Vitamin d in Obese

NCT05066490 | Completed

• 1 other identifier: HAP-02-T-067 428
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the current study was to investigate the effect of exercise-induced lipolysis on vitamin D status in obese children. Two types of exercises that have different effects on lipolysis were used. Lipolysis was assessed via monitoring the level of plasma level of the free fatty acids and glycerol. Vitamin D was assessed through 25 (OH)D plasma levels.

Conditions

Obesity; Vitamin D Deficiency

Outcome Measures

Primary Outcomes (3)

• Free fatty acids

  Plasma level of the free fatty acids immediatlly after the exercise.

  After 60 min of training

• Glycerol

  Plasma level of glycerol immediatlly after the exercise.

  After 60 min of training

• Vitamin D

  Plasma level of 25 (OH) D immediatlly after the exercise.

  After 60 min of training

Study Arms (2)

endurance exercise

EXPERIMENTAL

This group received endurance exercises only.

Other: Endurance exercise

resistance exersise plus endurance exersise

EXPERIMENTAL

This group received resistance exercises followed by endurance exercises.

Other: Endurance exercise; Other: Resistance exersises.

Interventions

Endurance exercise OTHER

Treadmill training at moderate intensity.

endurance exercise; resistance exersise plus endurance exersise

Resistance exersises. OTHER

Resistance exercises using the 10 repetition maximum.

resistance exersise plus endurance exersise

Eligibility Criteria

• Age: 7 Years - 10 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Body mass index percentile equal to or greater than the 95th percentile
• All did not receive strength or balance training or involvement in competitive sports emphasizing muscular strength.
• All participants had balance deficiency and mobile flat foot.
• (OH) D was ranged from 10-20ng/ml

You may not qualify if:

• Injury to the lower limb required medical care.
• Deformity of or surgery in the lower limb.
• Visual impairment, or neuromuscular disorders.
• Engagement in obesity treatment programs, three months prior to the study.
• Epileptic fits
• Thyroid medications
• Autoimmune disease
• Take calcium or vitamin d3 supplements, medications for osteoporosis

Sponsors & Collaborators

• Taif University: lead

Study Sites (1)

College of applied medical sciences

Ta'if, Mecca Region, 2425, Saudi Arabia

Location

MeSH Terms

Conditions

Obesity; Vitamin D Deficiency

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Avitaminosis; Deficiency Diseases; Malnutrition

Study Officials

• Hatem H Allam, Doctoral

  Assisstant professor

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Model Details: 40 obese children who suffered from vitamin d deficiency were randomly assigned into three groups. group I (15 children) received endurance exercises and group II (15 children) received endurance exercises preceded by resistance exercises which have a stronger lipolytic effect. group III (10 children) acted as a control group.

Study Record Dates

• First Submitted: September 22, 2021
• First Posted: October 4, 2021
• Study Start: October 6, 2020
• Primary Completion: February 15, 2021
• Study Completion: March 25, 2021
• Last Updated: January 11, 2022

Record last verified: 2021-12

Locations

SA (1)