Relationship Between Ambulatory Arterial Stiffness Index and Left Ventricular Diastolic Function in Patients With HFpEF
1 other identifier
observational
200
1 country
1
Brief Summary
Heart failure with preserved ejection fraction (HFpEF) was considered as a heterogeneous disease with multi-organ and multi-system design, which is related to various complications, such as hypertension, obesity and arteriosclerosis. Ambulatory arterial stiffness index (AASI) is associated with arteriosclerosis and hypertension. There is no report on whether AASI is associated with left ventricular diastolic dysfunction in patients with HFpEF.
Trial Health
Trial Health Score
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participants targeted
Target at P75+ for all trials
Started Oct 2020
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 10, 2020
CompletedStudy Start
First participant enrolled
October 10, 2020
CompletedFirst Posted
Study publicly available on registry
September 28, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2022
CompletedSeptember 28, 2021
September 1, 2021
1.2 years
October 10, 2020
September 26, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Left ventricular diastolic function
the ratio of mitral peak velocity of early filling to early diastolic mitral annular velocity(E/e')
1 day On admission
Eligibility Criteria
Heart failure patients with preserved ejection fraction (HFpEF)
You may qualify if:
- Adult aged \>=18years old; Diagnosed with HFpEF.
You may not qualify if:
- LVEF less than 45% at any time; Severe liver failure; Other causes of shortness of breath, such as severe pulmonary disease or severe Severe valvular disease of the left heart; Chronically bedridden or incapacitated; Age \<18 years old.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Dongying Zhanglead
Study Sites (1)
The first affiliated Hospital of Chongqing Medical University
Chongqing, 400042, China
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 7 Days
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Clinical Professor
Study Record Dates
First Submitted
October 10, 2020
First Posted
September 28, 2021
Study Start
October 10, 2020
Primary Completion
December 31, 2021
Study Completion
April 30, 2022
Last Updated
September 28, 2021
Record last verified: 2021-09
Data Sharing
- IPD Sharing
- Will not share