NCT05058729

Brief Summary

The primary objective of this sub-study is to supplement the Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) dataset with coronavirus disease 2019 (COVID-19)-related health information obtained from periodic participant questionnaires administered by participating MS PATHS institutions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,507

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2020

Shorter than P25 for all trials

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 7, 2020

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

September 27, 2021

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 28, 2021

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 8, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 8, 2021

Completed
Last Updated

April 18, 2023

Status Verified

April 1, 2023

Enrollment Period

10 months

First QC Date

September 27, 2021

Last Update Submit

April 14, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Completed COVID-19 Questionnaires Able to be Linked to a MS PATHS Participant Identifier (ID)

    Up to 17 months

Study Arms (1)

Cohort 1

Participants with multiple sclerosis (MS) or clinically isolated syndrome (CIS) who are enrolled in MS PATHS under Study 888MS001 and have completed at least one COVID-19 questionnaire administered by a participating healthcare institution.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants with MS or CIS who are enrolled in MS PATHS under Study 888MS001 and have completed at least one COVID-19 questionnaire administered by a participating healthcare institution will be included in this study.

You may qualify if:

  • Be enrolled in MS PATHS under Study 888MS001.
  • Completed one or more COVID-19 questionnaire at a participating MS PATHS institution.
  • Permission for data linkage either obtained when completing a local COVID-19 questionnaire or granted by waiver of informed consent from the local institutional review board (IRB) or ethics committee (EC).

You may not qualify if:

  • \. Other unspecified reasons that, in the opinion of the Investigator or Biogen, make the participant unsuitable for participation in the sub-study. A participant only needs to complete the assessments deemed necessary by the Investigator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Research Site

Baltimore, Maryland, 21287, United States

Location

Research Site

St Louis, Missouri, 63110, United States

Location

Research Site

Las Vegas, Nevada, 89106, United States

Location

Research Site

New York, New York, 10016, United States

Location

Research Site

Cleveland, Ohio, 44195, United States

Location

Research Site

Columbus, Ohio, 44195, United States

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Medical Director

    Biogen

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 27, 2021

First Posted

September 28, 2021

Study Start

December 7, 2020

Primary Completion

October 8, 2021

Study Completion

October 8, 2021

Last Updated

April 18, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will share

In accordance with Biogen's Clinical Trial Transparency and Data Sharing Policy on https://www.biogentrialtransparency.com/

More information

Locations