Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

19.9%

133 terminated/withdrawn out of 670 trials

Success Rate

77.7%

-8.8% vs industry average

Late-Stage Pipeline

26%

172 trials in Phase 3/4

Results Transparency

35%

163 of 464 completed trials have results

Key Signals

29 recruiting163 with results109 terminated24 withdrawn

Enrollment Performance

Analytics

Phase 1
197(37.7%)
Phase 2
132(25.3%)
Phase 3
110(21.1%)
Phase 4
62(11.9%)
N/A
19(3.6%)
Early Phase 1
2(0.4%)
522Total
Phase 1(197)
Phase 2(132)
Phase 3(110)
Phase 4(62)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (670)

Showing 20 of 670 trials
NCT07219043Phase 2Recruiting

A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

Role: lead

NCT05352919Phase 3Enrolling By Invitation

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Role: lead

NCT05531565Phase 2Active Not Recruiting

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Role: lead

NCT07221669Phase 3Recruiting

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Role: lead

NCT04317794Active Not Recruiting

Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

Role: lead

NCT07662148Phase 1Recruiting

A Study to Learn More About the Safety of a Single Dose of BIIB144 and How it is Processed in the Body of Healthy Adult Participants Ages 18 to 55 Years Old as Compared to a Placebo

Role: lead

NCT07722546Phase 2Not Yet Recruiting

A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old

Role: lead

NCT06935357Phase 3Recruiting

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

Role: lead

NCT06962800Phase 3Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

Role: lead

NCT06044337Phase 3Enrolling By Invitation

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Role: lead

NCT06628687Recruiting

A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies

Role: lead

NCT06454721Phase 1Completed

A Study to Determine the Biodistribution, Safety, and Tolerability of a Microdose of Radiolabeled Diranersen (BIIB080) Co-administered With Diranersen in Healthy Adults

Role: lead

NCT05575011Phase 1Active Not Recruiting

A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec

Role: lead

NCT07444489Phase 3Enrolling By Invitation

A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) or Microvascular Inflammation (MVI) (TRANSCEND/TRANSPIRE LTE)

Role: lead

NCT05399888Phase 2Active Not Recruiting

A Study to Learn About the Safety of Diranersen (BIIB080) Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

Role: lead

NCT07294144Phase 2Recruiting

Tofersen in Non-SOD1 ALS

Role: collaborator

NCT06953583Phase 3Recruiting

A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

Role: lead

NCT07444450Phase 3Not Yet Recruiting

A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec

Role: lead

NCT06685757Phase 3Active Not Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR)

Role: lead

NCT04468659Phase 3Active Not Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Role: collaborator