Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

19.9%

133 terminated/withdrawn out of 668 trials

Success Rate

77.7%

-8.8% vs industry average

Late-Stage Pipeline

26%

172 trials in Phase 3/4

Results Transparency

35%

163 of 464 completed trials have results

Key Signals

29 recruiting163 with results109 terminated24 withdrawn

Enrollment Performance

Analytics

Phase 1
196(37.7%)
Phase 2
131(25.2%)
Phase 3
110(21.2%)
Phase 4
62(11.9%)
N/A
19(3.7%)
Early Phase 1
2(0.4%)
520Total
Phase 1(196)
Phase 2(131)
Phase 3(110)
Phase 4(62)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (668)

Showing 20 of 668 trials
NCT06962800Phase 3Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

Role: lead

NCT05352919Phase 3Enrolling By Invitation

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Role: lead

NCT06935357Phase 3Recruiting

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

Role: lead

NCT07294144Phase 2Recruiting

Tofersen in Non-SOD1 ALS

Role: collaborator

NCT07221669Phase 3Recruiting

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Role: lead

NCT07219043Phase 2Recruiting

A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

Role: lead

NCT07444450Phase 3Not Yet Recruiting

A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec

Role: lead

NCT05399888Phase 2Active Not Recruiting

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

Role: lead

NCT06685757Phase 3Active Not Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR)

Role: lead

NCT04468659Phase 3Active Not Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Role: collaborator

NCT05688436Active Not Recruiting

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Role: lead

NCT05348785Phase 2Completed

A Study to Learn About the Safety of BIIB122 Tablets and Whether They Can Slow the Worsening of Early-Stage Parkinson's Disease in Adults Between the Ages of 30 and 80

Role: lead

NCT02454907Not ApplicableCompleted

The Use of Technology to Improve MS Clinical Trials and Patient Care

Role: collaborator

NCT06953583Phase 3Recruiting

A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

Role: lead

NCT03681015Completed

Wearable Assessments in the Clinic and Home in PD

Role: collaborator

NCT06602193Phase 2Active Not Recruiting

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

Role: collaborator

NCT06741657Phase 1Completed

A Study to Find Out How Litifilimab is Processed in the Body in Healthy Participants When Given Under the Skin in 3 Different Ways

Role: lead

NCT05067790Phase 3Active Not Recruiting

A Study to Learn About the Effect of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Risdiplam (ASCEND)

Role: lead

NCT02283853Phase 3Completed

Phase 3 Efficacy and Safety Study of BG00012 in Pediatric Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

Role: lead

NCT07297199Phase 1Completed

A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55

Role: lead