NCT05056207

Brief Summary

This research study is to learn about breast cancer patients' opinions about screening for lymphedema (a side effect of breast cancer treatment in which the arm can become heavy, painful, and/or swollen) and their satisfaction with the lymphedema screening program.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
260

participants targeted

Target at P75+ for not_applicable

Timeline
6mo left

Started Nov 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress95%
Nov 2017Nov 2026

Study Start

First participant enrolled

November 17, 2017

Completed
3.8 years until next milestone

First Submitted

Initial submission to the registry

September 15, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 24, 2021

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 17, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 17, 2026

Last Updated

March 5, 2026

Status Verified

March 1, 2026

Enrollment Period

9 years

First QC Date

September 15, 2021

Last Update Submit

March 3, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • To establish the effectiveness of prospective, intensive lymphedema screening in the postoperative setting using a perometer.

    through study completion, an average of 1 year

Study Arms (2)

Cohort I (patients receiving annual lymphedema screening)

OTHER

We will retrospectively retrieve information on patients who previously underwent preoperative perometer lymphedema screening during the past year who were treated definitively for their breast cancer with an ALND, and for whom no follow-up postoperative lymphedema screening was done.

Other: Cohort I (patients receiving annual lymphedema screening

Cohort II (patients followed intensively for lymphedema)

OTHER

We will prospectively follow a cohort of 279 patients who have recently undergone ALND in this upcoming year with intensive lymphedema screening.

Other: Cohort II (patients followed intensively for lymphedema)

Interventions

patientns who previously underwent preoperative perometer lymphedema screening

Cohort I (patients receiving annual lymphedema screening)

patients who have recently undergone ALND

Cohort II (patients followed intensively for lymphedema)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • a Cohort A:
  • Breast cancer patients with a baseline (preoperative perometer measurements) who have undergone axillary lymph node dissection
  • English speaker
  • Patients who participate in Cohort A will be eligible for enrollment in Cohort
  • b Cohort I:
  • Breast cancer patients who have undergone axillary lymph node dissection who have a clinic visit in the Nellie B. Connally Breast Center approximately 12 months (+/- 4 months) following axillary lymph node dissection
  • English speaker
  • c Cohort II:
  • Breast cancer patients who have undergone axillary lymph node dissection who are having a follow-up visit in the Nellie B. Connally Breast Center within 0-6 months following surgery who intend to continue follow-up care at MD Anderson
  • English speaker

You may not qualify if:

  • Inability to complete a self-administered questionnaire

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Conditions

Lymphedema

Condition Hierarchy (Ancestors)

Lymphatic DiseasesHemic and Lymphatic Diseases

Study Officials

  • Simona Shaitelman

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2021

First Posted

September 24, 2021

Study Start

November 17, 2017

Primary Completion (Estimated)

November 17, 2026

Study Completion (Estimated)

November 17, 2026

Last Updated

March 5, 2026

Record last verified: 2026-03

Locations