Eccentric Versus Concentric Exercises for Rotator Cuff Tendinopathy in Patients With Rheumatoid Arthritis

NCT05054920 | Completed

• 1 other identifier: Mina
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Study aiming at determining the efficacy of eccentric versus concentric exercises for improving tendon biological characteristics, pain, and shoulder overall function for rotator cuff tendinopathy in patients with Rheumatoid arthritis (RA). Moreover, investigation the relationship between RA activity and the severity of rotator cuff tendinopathy. Patients will be randomly assigned into either concentric or eccentric exercise group. Randomizations will be done using computer random generated numbers.

Conditions

Rheumatoid Arthritis; Rotator Cuff Tendinosis; Tendinopathy

Outcome Measures

Primary Outcomes (1)

• Shoulder function

  shoulder Pain and Disability Index (SPADI): It is a self-reported questionnaire evaluating the function of the shoulder.

  one month

Secondary Outcomes (5)

• tendon thickness, fibrillar pattern and echogenicity

  one month

• subacromial space

  one month

• Pain measured by Visual analogue scale (VAS)

  one month

• ESR

  one month

• disease activity score 28 Erythrocyte sedimentation rate (DAS 28- ESR)

  one month

Study Arms (2)

Concentric exercises group

EXPERIMENTAL

patient will do Concentric exercises. Patients will receive 3 sessions per week for 4 weeks. Exercise will be done under the supervision of the same physical therapist. During each session. Exercise will be in the form of glenohumeral scaption, internal and external rotation exercises. patient will also do stretching for posterior capsule and pectoralis minor

Other: concentric exercises; Other: Stretching

Eccentric exercises group

EXPERIMENTAL

patient will do eccentric exercises. Patients will receive 3 sessions per week for 4 weeks. Exercise will be done under the supervision of the same physical therapist during each session. Exercise will be in the form of glenohumeral scaption, internal and external rotation exercises. patient will also do stretching for posterior capsule and pectoralis minor

Other: eccentric exercises; Other: Stretching

Interventions

concentric exercises OTHER

concentric exercises for rotator cuff. internal rotators, external rotators and abductors Patient will do 3 sets of 10 repetitions resistance will be personalized to each patients

Concentric exercises group

eccentric exercises OTHER

Eccentric exercises exercises for rotator cuff internal rotators, external rotators and abductors Patient will do 3 sets of 10 repetitions resistance will be personalized to each patients

Eccentric exercises group

Stretching OTHER

stretching exercise for posterior capsule and pectoralis minor each stretch will be done for 30 seconds and repeated 3 times

Concentric exercises group; Eccentric exercises group

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Adult patients diagnosed with RA according to 2010 (American College of Rheumatology)(ACR)/European League Against Rheumatism (EULAR) Classification Criteria for RA
• Patients diagnosed with rotator cuff tendinopathy based on clinical and musculoskeletal Ultrasonography (MSUS) finding.
• Patient complaining of shoulder pain for at least 3 months
• Positive jobs test or hornblower sign or left off test
• Age ranged from 18 to 50 years.

You may not qualify if:

• Patient indicated for surgical repair of rotator cuff
• Patient with previous shoulder surgery.
• Patient with history of intra-articular shoulder fracture.
• Patient with history of shoulder dislocation
• Diabetes mellitus

Sponsors & Collaborators

• Cairo University: lead
• Badr University: collaborator

Study Sites (1)

Badr University in Cairo (BUC)

Cairo, 12311, Egypt

Location

MeSH Terms

Conditions

Arthritis, Rheumatoid; Rotator Cuff Injuries; Tendinopathy

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases; Rupture; Wounds and Injuries; Shoulder Injuries; Tendon Injuries; Muscular Diseases

Study Officials

• Mohammed Shawki Abdelsalam, PhD

  Assistance Professor,Faculty of Physical Therapy Cairo University

  STUDY CHAIR

• Mona Fagaal, PhD

  Assistance Professor, Faculty of Physical Therapy Badr University in Cairo

  STUDY DIRECTOR

• Mohammed Moustafa Aldosouki Hegazy, PhD

  Lecturer,Faculty of Physical Therapy Cairo University

  STUDY DIRECTOR

• Rasmia Mohamed Hassan ElGohry, phD

  Cairo University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: September 19, 2021
• First Posted: September 23, 2021
• Study Start: September 30, 2021
• Primary Completion: April 1, 2022
• Study Completion: September 1, 2022
• Last Updated: September 6, 2023

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)