Village Malaria Worker Expansion

NCT05045547 | Completed

• 1 other identifier: HCR21005
• Study Type: observational
• Target: 7,191
• Locations: 1 country
• Sites: 1

Brief Summary

This project will conduct pragmatic operational research in rural communities served by approximately 12 health centres and 120 village malaria workers in Battambang/Pailin, western Cambodia. This study is funded by Global Fund/Regional Artemisinin Initiative (RAI3E). The grant reference number is QSE-M-UNOPS-MORU-20864-007-42

Conditions

Febrile Illness

Keywords

Febrile Illness; Village Health Worker; Cambodia

Outcome Measures

Primary Outcomes (1)

• The number of VMW consultations by patients

  The number of VMW consultations by patients with a febrile and/or non-febrile illness along with the number of malaria RDTs used will be recorded. Comparing these data across the different intervention packages introduced for VMWs.

  Approximately 18-24 months

Secondary Outcomes (8)

• The number of VMWs that can correctly perform RDTS following a directly observed practical assessment and questionnaire.

  Approximately 18-24 months

• The number of VMWs who correctly follow the treatment algorithms following a directly observed practical assessment and questionnaire.

  Approximately 18-24 months

• The overall consensus of stakeholders regarding the new roles of VMWs following stakeholder interviews

  0 months, mid-point of the study (12 months) and at study completion (24 months)

• The overall consensus of stakeholders of the impact on non-malarial febrile illness management following stakeholder interviews

  0 months, mid-point of the study (12 months) and at study completion (24 months)

• The number of VMWs that can correctly deliver one of four health intervention packages following a directly observed practical assessment and questionnaire.

  0 months, mid-point of the study (12 months) and at study completion (24 months)

Other Outcomes (1)

• The number of patients appropriately referred for further care

  Approximately 18-24 months

Study Arms (3)

Patients with febrile illness

Febrile patients attending village malaria workers (VMWs)

Health centre staffs

Health centre staffs from 12 rural health centres

Key stakeholders

Key stakeholders , for example health managers and health professionals: * the director, deputy-directors, and technical officers at the National Malaria Control Program; * the directors and deputy-directors of the Provincial Health Departments in Battambang and Pailin province; * health officers actively involved in community-based (malaria) programmes at the district levels in Battambang and Pailin provinces; * health workers (i.e., nurses or doctors) actively involved in community-based (malaria) programmes in Battambang and Pailin provinces; * community representatives and village malaria workers from villages in both Battambang Pailin province.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

1. Quantitative research Participants: Febrile patients attending village malaria workers (VMWs) 2. Qualitative research 2.1 Health centre-based evaluation of novel diagnostics Participants: Health centre staffs from 12 rural health centres 2.2 Stakeholder analysis Participants: Key stakeholders , for example health managers and health professionals: * the director, deputy-directors, and technical officers at the National Malaria Control Program; * the directors and deputy-directors of the Provincial Health Departments in Battambang and Pailin province; * health officers actively involved in community-based (malaria) programmes at the district levels in Battambang and Pailin provinces; * health workers (i.e., nurses or doctors) actively involved in community-based (malaria) programmes in Battambang and Pailin provinces; * community representatives and village malaria workers from villages in both Battambang Pailin province.

You may qualify if:

• Quantitative research
• Written informed consent
• Willingness to provide blood sample
• Fever (≥37.5 C) or history of fever within 24 hours
• Qualitative research
• Health centre-based evaluation of novel diagnostics
• Health centre staff who have received training in the use of the novel diagnostics used in the study
• Willing and able to give informed consent for participation in the study
• Stakeholder analysis
• Adults, male or female, aged 18 years and over
• Willing and able to give informed consent for participation in the study

You may not qualify if:

• Quantitative research
• Participants requires urgent medical attention
• Qualitative research
• Identified with intellectual and/or cognitive disability
• History of or current psychiatric illness

Sponsors & Collaborators

• University of Oxford: lead
• Mahidol Oxford Tropical Medicine Research Unit: collaborator

Study Sites (1)

Action for Health and Development

Battambang, Cambodia

Location

Study Officials

• Thomas J Peto, Dr.

  Mahidol Oxford Tropical Medicine Research Unit

  PRINCIPAL INVESTIGATOR

• James J Callery, Dr.

  Mahidol Oxford Tropical Medicine Research Unit

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2021
• First Posted: September 16, 2021
• Study Start: April 17, 2022
• Primary Completion: June 30, 2023
• Study Completion: June 30, 2023
• Last Updated: March 19, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share
• Time Frame: After completion of trial activities and reporting
• Access Criteria: MORU Data Sharing Policy. (http://www.tropmedres.ac/data-sharing-policy)

Locations

CA (1)