Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders

NCT05045157 | Recruiting

• 1 other identifier: CHD21_0024
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 4

Brief Summary

Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion. Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection. If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed. Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance). Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia. The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms

Conditions

Trigger Finger

Outcome Measures

Primary Outcomes (1)

• Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms

  Trigger finger's symptoms defined by a clinical Quinnell score ≤1 without the use of an alternative therapy

  1 year postoperatively

Study Arms (2)

percutaneous A1 pulley release with corticosteroid injection

EXPERIMENTAL

Procedure: Percutaneous A1 Pulley Release Under Ultrasound Guidance; Drug: Corticosteroid injection

corticosteroid injection alone

ACTIVE COMPARATOR

Drug: Corticosteroid injection

Interventions

Percutaneous A1 Pulley Release Under Ultrasound Guidance PROCEDURE

the A1 pulley is cut off with Ultrasound guidance by a percutaneous insertion of the small needle under local anaesthesia.

percutaneous A1 pulley release with corticosteroid injection

Corticosteroid injection DRUG

corticosteroid injection is performed

corticosteroid injection alone; percutaneous A1 pulley release with corticosteroid injection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient ≥ 18 years old,
• Presence of a trigger finger (thumb or long fingers) to be treated
• Quinnell score \>1
• Episode of trigger characterized on questioning or clinical examination
• Thickening A1 pulley on ultrasound ≥ 0.5 mm
• Patient who has the capacity to understand the protocol and has given consent to participate in the research,
• Patient with social security coverage

You may not qualify if:

• Presence of several symptomatic fingers requiring treatment by ultrasound-guided section of the pulley
• Known allergy to corticoid (Hydrocortancyl®) including its excipients ((benzyl alcohol, sodium carmellose, sodium chloride, polysorbate 80)
• Known allergies to lidocaine
• Ongoing anticoagulant treatments (AVK, New Oral Anti-Coagulants)
• Local or general infection, or suspicion of infection
• Live vaccines
• Evolving viruses (hepatitis, herpes, varicella, shingles)
• Severe or uncontrolled hypertension
• Unbalanced diabetes
• Underlying progressive cardiovascular disease
• Hemodialysis patients
• Prosthesis on the finger to be treated
• Echographic tendon fissure
• Inflammatory disease (rheumatoid arthritis, spondyloarthritis, connective tissue diseases, etc.) with tenosynovitis.
• History of surgery on the fingers

Sponsors & Collaborators

• Centre Hospitalier Departemental Vendee: lead

Study Sites (4)

Hopital Henri Mondor

Créteil, 94000, France

RECRUITING

CHD Vendée

La Roche-sur-Yon, 85925, France

RECRUITING

CHU Nantes

Nantes, 44000, France

RECRUITING

Hopital Lariboisière

Paris, 75010, France

RECRUITING

MeSH Terms

Conditions

Trigger Finger Disorder

Interventions

Adrenal Cortex Hormones

Condition Hierarchy (Ancestors)

Tendon Entrapment; Tendinopathy; Muscular Diseases; Musculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists

Study Officials

• Grégoire Cormier, Dr

  CHD Vendée

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Clémentin GABORIAU

CONTACT

02 51 44 65 72; clementin.gaboriau@ght85.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 7, 2021
• First Posted: September 16, 2021
• Study Start: May 31, 2022
• Primary Completion (Estimated): May 31, 2026
• Study Completion (Estimated): May 31, 2027
• Last Updated: September 23, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (4)