Genome-wide Association Study of Development of Collateral Circulation for Patients With Coronary or Peripheral Artery Disease
GWAScollateral
1 other identifier
observational
400
1 country
1
Brief Summary
The purpose of this study is to evaluate the genome-wide association for the development of collateral circulation for patients with coronary or peripheral artery disease and to develop the molecular genetic treatment model based on genome-wide association data.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2015
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 21, 2015
CompletedFirst Submitted
Initial submission to the registry
September 12, 2021
CompletedFirst Posted
Study publicly available on registry
September 14, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2025
CompletedSeptember 14, 2021
September 1, 2021
9.9 years
September 12, 2021
September 12, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Correlation between genome and collateral flow
5 years
Study Arms (4)
Coronary Artery Disease_collateral flow grade 2
Coronary Artery Disease_collateral flow grade 0
Peripheral Artery Disease_collateral flow grade 2
Peripheral Artery Disease_collateral flow grade 0
Interventions
for evaluation of the genome-wide association study
Eligibility Criteria
Patients with chronic total coronary or peripheral occlusion
You may qualify if:
- Age more than 20
- Chronic total occlusive lesion from the coronary or peripheral angiogram
You may not qualify if:
- Renal dysfunction
- Hepatic dysfunction
- Thrombocythemia or thrombocythemia
- Planned major surgery in 1 year
- History of gastrointestinal haemorrhage
- Malignant tumor
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Jung-min Ahnlead
Study Sites (1)
Asan Medical Center
Seoul, South Korea
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
September 12, 2021
First Posted
September 14, 2021
Study Start
August 21, 2015
Primary Completion
June 30, 2025
Study Completion
December 31, 2025
Last Updated
September 14, 2021
Record last verified: 2021-09