NCT05043207

Brief Summary

The objective of this study is to validate the User-operated Audiometry (UAud) system for user-operated audiometry in a clinical setting, by investigating if hearing rehabilitation based on UAud is non-inferior to hearing rehabilitation based on traditional audiometry, and whether thresholds obtained with the user-operated version of the Audible Contrast Threshold (ACT) test correlates to traditional measures of speech intelligibility.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 30, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 14, 2021

Completed
12 months until next milestone

Study Start

First participant enrolled

September 1, 2022

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

November 15, 2023

Status Verified

November 1, 2023

Enrollment Period

1 year

First QC Date

August 30, 2021

Last Update Submit

November 14, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • SSQ12 (Speech, Spatial & Qualities of Hearing scale)

    A questionnaire reflecting the patient's subjective assessment of hearing in everyday life.

    3 months

Secondary Outcomes (1)

  • HINT (Hearing In Noise Test)

    3 months

Other Outcomes (4)

  • IOI-HA (International Outcome Inventory for Hearing Aids)

    3 months

  • APHAB (Abbreviated Profile of Hearing Aid Benefit).

    3 months

  • HINT-U (Hearing In Noise test - under amplification)

    3 months.

  • +1 more other outcomes

Study Arms (2)

uAud

EXPERIMENTAL

Patients which hearing aid is fitted based on the audiometry obtained with user-operated automated audiometry.

Diagnostic Test: uAud

control

ACTIVE COMPARATOR

Patients which hearing aid is fitted based on the audiometry obtained with traditional audiometry.

Diagnostic Test: Traditional audiometry

Interventions

uAudDIAGNOSTIC_TEST

Patients will receive hearing aid treatment based on an audiometry obtained with an user-operated automated audiometry procedure

uAud
Traditional audiometryDIAGNOSTIC_TEST

Patients will receive hearing aid treatment based on an audiometry obtained with an traditional audiometry procedure

control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Sensorineural hearing loss with hearing thresholds exceeding 20 dB HL at two or more frequencies in the frequency range of 0.5 to 4 kHz.
  • Symmetric hearing loss with a maximum pure-tone average (PTA) (mean of 0.5-1-2-4 kHz) difference between the ears of 15 dB HL.
  • Danish native speaker.
  • No previous experience with HAs.
  • Capable of answering questionnaires through an online mailbox.

You may not qualify if:

  • Air-conduction audiometry thresholds exceeding 80 dB HL at two or more frequencies.
  • Treatment affected by conductive hearing loss (air-bone gap \>10 dB on more than one frequency below 1 kHz).
  • Conditions with fluctuating hearing loss, e.g., Menière's, on-going treatment with ototoxic drugs.
  • Ear, nose, or throat surgery in the past 12 months.
  • Evidence that the participant has made minor use of the HAs during the study (e.g., \< 2h per day).
  • Visual or motor impairment that might affect the use of the UAud system.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Southern Denmark

Odense, Funen, 5000, Denmark

RECRUITING

Related Publications (2)

  • Pedersen C, Pedersen ER, Laugesen S, Sanchez-Lopez R, Nielsen J, Sorensen CB, Schmidt JH. Comparison of hearing-aid effectiveness based on user-operated versus traditional audiometry: a randomised clinical trial. Int J Audiol. 2024 Dec 2:1-8. doi: 10.1080/14992027.2024.2434897. Online ahead of print.

  • Pedersen CC, Pedersen ER, Laugesen S, Sanchez-Lopez R, Nielsen J, Sorensen CB, Sidiras C, Pedersen RG, Schmidt JH. Comparison of hearing aid fitting effectiveness with audiograms from either user-operated or traditional audiometry in a clinical setting: a study protocol for a blinded non-inferiority randomised controlled trial. BMJ Open. 2023 Mar 2;13(3):e065777. doi: 10.1136/bmjopen-2022-065777.

MeSH Terms

Conditions

Hearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jesper Hvass Schmidt, PhD

    SDU

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Carl Pedersen, master's degree

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Masking Details
The HA fitting procedure will be blinded, so neither the participant, the audiologist, nor the follow up test examiner knows which group the participant belongs to.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: randomised control trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 30, 2021

First Posted

September 14, 2021

Study Start

September 1, 2022

Primary Completion

September 1, 2023

Study Completion

December 1, 2024

Last Updated

November 15, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Data is governed by the hospital's GPDR (General Data Protection Regulation) agreements.

Locations