Biobank for Inflammatory Chronic Diseases and Osteoporosis

NCT05039216 | Recruiting

• 1 other identifier: RC31/21/0163
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to constitute a biobank for patients followed in the Rheumatology center of Toulouse University Hospital for a chronic inflammatory rheumatism including rheumatoid arthritis (RA), spondyloarthritis(SpA), and psoriatic arthritis (PsA) or a chronic bone disease including osteoporosis in order to identify biomarkers associated with therapeutic response.

Conditions

Rheumatoid Arthritis; Psoriatic Arthritis; Spondyloarthritis; Osteoporosis

Outcome Measures

Primary Outcomes (1)

• EULAR response after 3 months

  EULAR response after 3 months

  after 3 months

Study Arms (2)

patients initiating a biotherapy or a target treatment

Blood sampling

Biological: Blood sampling

patients with chronic inflammatory rheumatism, weakening osteopathy or mechanical pathology

Blood sampling

Biological: Blood sampling

Interventions

Blood sampling BIOLOGICAL

4 tubes of 7 mL will be sampled

patients initiating a biotherapy or a target treatment; patients with chronic inflammatory rheumatism, weakening osteopathy or mechanical pathology

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

monocentric observational longitudinal study

You may qualify if:

• Chronic inflammatory rheumatism including RA, SpA or PsA or patients with primary or secondary osteoporosis
• With National Health Assurance
• Able to consent to the study

You may not qualify if:

• Pregnancy or breastfeeding
• Not able to give a consent
• Severe anemia (Hb\<10g/L)

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

Purpan University Hospital

Toulouse, 31059, France

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Blood

MeSH Terms

Conditions

Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylarthritis; Osteoporosis

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases; Spondylarthropathies; Spondylitis; Spinal Diseases; Bone Diseases; Psoriasis; Skin Diseases, Papulosquamous; Skin Diseases; Bone Diseases, Metabolic; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Officials

• Adeline RUYSSEN-WITRAND, MD

  University Hospital, Toulouse

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Adeline RUYSSEN-WITRAND, MD

CONTACT

561775626; ruyssen-witrand.a@chu-toulouse.fr

Delphine THUILLEZ

CONTACT

561776966; thuillez.d@chu-toulouse.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 6, 2021
• First Posted: September 9, 2021
• Study Start: September 13, 2021
• Primary Completion (Estimated): September 2, 2026
• Study Completion (Estimated): September 1, 2031
• Last Updated: March 19, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)