NCT05039112

Brief Summary

The purpose of this study to evaluate the overall performance of PRECISION1™ for Astigmatism contact lenses with MyDay® Toric contact lenses.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 31, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 9, 2021

Completed
19 days until next milestone

Study Start

First participant enrolled

September 28, 2021

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 29, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 29, 2021

Completed
Last Updated

December 7, 2021

Status Verified

December 1, 2021

Enrollment Period

2 months

First QC Date

August 31, 2021

Last Update Submit

December 6, 2021

Conditions

Keywords

Contact lensesDaily disposable

Outcome Measures

Primary Outcomes (1)

  • Percent of lenses with axis orientation within ±30 degrees inclusive from the intended axis, 10 minutes after lens insertion

    Axis orientation (orientation of the scribe mark) will be assessed by slit lamp examination and recorded as deviations from intended axis.

    Day 1, 10 minutes after lens insertion, each product

Study Arms (2)

P1fA, then MyDay Toric

OTHER

Verofilcon A toric contact lenses worn first, with stenfilcon A toric contact lenses worn second, as randomized. Each product will be worn bilaterally (in both eyes) for 8 (-0/+3) days in a daily disposable modality.

Device: Verofilcon A toric contact lensesDevice: Stenfilcon A toric contact lenses

MyDay Toric, then P1fA

OTHER

Stenfilcon A toric contact lenses worn first, with verofilcon A toric contact lenses worn second, as randomized. Each product will be worn bilaterally (in both eyes) for 8 (-0/+3) days in a daily disposable modality.

Device: Verofilcon A toric contact lensesDevice: Stenfilcon A toric contact lenses

Interventions

Soft contact lenses for optical correction of astigmatism, used as indicated

Also known as: PRECISION1 for Astigmatism, P1fA
MyDay Toric, then P1fAP1fA, then MyDay Toric

Soft contact lenses for optical correction of astigmatism, used as indicated

Also known as: MyDay Toric
MyDay Toric, then P1fAP1fA, then MyDay Toric

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Successful wear of toric soft contact lenses in both eyes for a minimum of 5 days per week and 10 hours per day during the past 3 months.
  • Willing to wear study contact lenses for at least 16 hours on the day prior to the Week 1 Follow up visit of each lens type.

You may not qualify if:

  • Current/previous wear of PRECISION1 for Astigmatism or MyDay Toric contact lenses.
  • Current wear of spherical contact lenses.
  • Wears habitual contact lenses in an extended wear modality (routinely sleeping in lenses for at least 1 night per week).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Alcon Investigator 6565

Maitland, Florida, 32751, United States

Location

Alcon Investigator 6567

Pittsburg, Kansas, 66762, United States

Location

Alcon Investigator 8097

Sterling Heights, Michigan, 48312, United States

Location

Alcon Investigator 6313

Powell, Ohio, 43065, United States

Location

Alcon Investigator 6401

Warwick, Rhode Island, 02888, United States

Location

Alcon Investigator 6353

Memphis, Tennessee, 38111, United States

Location

MeSH Terms

Conditions

Refractive ErrorsAstigmatism

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

  • Clinical Trial Lead, Vision Care

    Alcon Research, LLC

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 31, 2021

First Posted

September 9, 2021

Study Start

September 28, 2021

Primary Completion

November 29, 2021

Study Completion

November 29, 2021

Last Updated

December 7, 2021

Record last verified: 2021-12

Data Sharing

IPD Sharing
Will not share

Locations