China Kidney Patient Trials Network
CKPTN
1 other identifier
observational
1,200
1 country
1
Brief Summary
This is a prospective multi-centre, observational cohort study of incident and prevalent patients diagnosed with a kidney disease in China.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2021
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 27, 2021
CompletedFirst Posted
Study publicly available on registry
September 8, 2021
CompletedStudy Start
First participant enrolled
September 27, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 15, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
February 28, 2031
March 6, 2023
March 1, 2023
5 years
August 27, 2021
March 3, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
eGFR (estimated Glomerular Filtration Rate)
Routine results
Collected six monthly, up to 5 years
Albuminuria
Routine results
Collected six monthly, up to 5 years
Study Arms (1)
Incident and Prevalent Patients
Incident and prevalent patients diagnosed with a kidney disease at participating centres
Eligibility Criteria
Participants will be recruited from units that provide a comprehensive nephrology service
You may qualify if:
- Documented diagnosis of primary kidney disease
- Regular visits (at least 6 monthly) with a physician at a participating site
- eGFR \> 15 ml/min/1.73 m2
- ≥ 2 years of age
- Willing and able to sign informed consent
- Willing to be approached about participation in interventional research studies
You may not qualify if:
- \. Life-expectancy of less than 6 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
George Clinical (Beijing)
Beijing, Beijing Municipality, 100125, China
Related Publications (7)
Luyckx VA, Tonelli M, Stanifer JW. The global burden of kidney disease and the sustainable development goals. Bull World Health Organ. 2018 Jun 1;96(6):414-422D. doi: 10.2471/BLT.17.206441. Epub 2018 Apr 20.
PMID: 29904224BACKGROUNDTonelli M, Muntner P, Lloyd A, Manns BJ, Klarenbach S, Pannu N, James MT, Hemmelgarn BR; Alberta Kidney Disease Network. Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study. Lancet. 2012 Sep 1;380(9844):807-14. doi: 10.1016/S0140-6736(12)60572-8. Epub 2012 Jun 19.
PMID: 22717317BACKGROUNDGo AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004 Sep 23;351(13):1296-305. doi: 10.1056/NEJMoa041031.
PMID: 15385656BACKGROUNDMcGrogan A, Franssen CF, de Vries CS. The incidence of primary glomerulonephritis worldwide: a systematic review of the literature. Nephrol Dial Transplant. 2011 Feb;26(2):414-30. doi: 10.1093/ndt/gfq665. Epub 2010 Nov 10.
PMID: 21068142BACKGROUNDStrippoli GF, Craig JC, Schena FP. The number, quality, and coverage of randomized controlled trials in nephrology. J Am Soc Nephrol. 2004 Feb;15(2):411-9. doi: 10.1097/01.asn.0000100125.21491.46.
PMID: 14747388BACKGROUNDPerkovic V, Craig JC, Chailimpamontree W, Fox CS, Garcia-Garcia G, Benghanem Gharbi M, Jardine MJ, Okpechi IG, Pannu N, Stengel B, Tuttle KR, Uhlig K, Levey AS. Action plan for optimizing the design of clinical trials in chronic kidney disease. Kidney Int Suppl (2011). 2017 Oct;7(2):138-144. doi: 10.1016/j.kisu.2017.07.009. Epub 2017 Sep 20.
PMID: 30675428BACKGROUNDde Zeeuw D, Heerspink HJL, Jardine M, Perkovic V. Renal trials in diabetes need a platform: time for a global approach? Lancet Diabetes Endocrinol. 2018 May;6(5):356-358. doi: 10.1016/S2213-8587(17)30263-2. Epub 2017 Aug 7. No abstract available.
PMID: 28797748BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Years
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 27, 2021
First Posted
September 8, 2021
Study Start
September 27, 2021
Primary Completion (Estimated)
September 15, 2026
Study Completion (Estimated)
February 28, 2031
Last Updated
March 6, 2023
Record last verified: 2023-03
Data Sharing
- IPD Sharing
- Will not share
The current plan is that only aggregate data will be shared for research purposes. IPD would only be reviewed in incidental findings and only be discussed with the participant in question.