A Prediction Model of Hematological Recovery After High-dose Chemotherapy in Pediatric Solid Tumor

NCT05024331 | Completed

• 1 other identifier: 2021-02-059
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare and evaluate the predicted values of the participants, and the algorithm predicted values of ANC level reduction periods after high-capacity chemotherapy in pediatric solid tumor patients. The participants are pediatricians who voluntarily participate in this study and consent to this study.

Conditions

Pediatric Solid Tumor

Keywords

oncology; prediction model; hematological recovery

Outcome Measures

Primary Outcomes (2)

• accuracy of algorithm

  primary outcome is the difference between result of algorithm and prediction values of doctors. total number of pediatric patients who performed chemotherapy and high-capacity chemotherapy at Samsung Medical Center in 2019-2020 - (Exclusion such as insufficient data or death) +10 reliability check questions expected to be approximately 100 questions The test based on data consisting of blood test results from approximately 100 patients, is recorded in anticipation of the first date (recovery date) of a day when ANC levels over 500 last more than 3 days.

  This clinical trial is conducted in one day, and the Survey is conducted after completing the test using data from 99 pediatric patients.

• A quantitative study on usability

  We would like to ask 17 questions to identify the user's thoughts on AI and how they affect change of opinion. The following are examples are as follows: Do you think you can easily adapt to new technologies or programs? Do you value subjective thoughts and experiences over other people's opinions in your work? Do you tend to browse information online when making decisions during work? Apart from this study, are you positive about the use of predictive models in clinical trials? Do you think the items and information in the given data are sufficient to predict the values you want to predict?

  This clinical trial is conducted in one day, and the Survey is conducted after completing the test using data from 99 pediatric patients.

Study Arms (1)

Pediatric physicians

Assigned Interventions 1. Prediction of the first date of recovery period with given data about chemotherapy of pediatric patients who diagnosed solid tumor at Samsung medical center during 2010-2018 2. Sees the result of the prediction algorithm. 3. Change or maintain their prediction values. 4. Participate in the usability questionnaires.

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

a physician who is working at Samsung Medical Center as a pediatric doctor

You may qualify if:

• physician who is working at Samsung Medical Center as a pediatric doctor
• A person who voluntarily agrees to participate in the study

You may not qualify if:

• Those who disagree with the study

Sponsors & Collaborators

• Samsung Medical Center: lead

Study Sites (1)

Samsung Medical Centre

Seoul, 06351, South Korea

Location

MeSH Terms

Conditions

Neoplasms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 10, 2021
• First Posted: August 27, 2021
• Study Start: July 30, 2021
• Primary Completion: July 30, 2021
• Study Completion: August 12, 2021
• Last Updated: September 13, 2021

Record last verified: 2021-07

Locations

KR (1)