Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.3%

1 terminated out of 23 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

17%

1 of 6 completed with results

Key Signals

1 with results86% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (1)
P 1 (13)
P 2 (3)

Trial Status

Recruiting7
Completed6
Active Not Recruiting5
Unknown3
Terminated1
Not Yet Recruiting1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT02520713Active Not RecruitingPrimary

The iCat2, GAIN (Genomic Assessment Informs Novel Therapy) Consortium Study

NCT04483778Phase 1Active Not RecruitingPrimary

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT03739827Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

NCT04222413Phase 1Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

NCT04897321Phase 1RecruitingPrimary

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT05521984Phase 1Recruiting

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

NCT03478462Phase 1Active Not RecruitingPrimary

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

NCT05468359Phase 1Recruiting

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

NCT07358260Phase 1Not Yet RecruitingPrimary

B7-H3.CD28Z.CART in Solid Tumors

NCT03618381Phase 1Active Not RecruitingPrimary

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT05151718Recruiting

Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents

NCT04239040Phase 1Terminated

GVAX Plus Checkpoint Blockade in Neuroblastoma

NCT06760117Phase 1RecruitingPrimary

UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors

NCT05620862Phase 1Active Not RecruitingPrimary

Phase I Dose Escalation and Pharmacokinetics Clinical Trial of Mitoxantrone Hydrochloride Liposome in Children With Relapsed and Refractory Lymphoma and Solid Tumors

NCT03455140Phase 1Completed

A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)

NCT05322187Phase 2Unknown

Sequential PD-1/PD-L1 Inhibitor and LENvatinib in TLCT and Refractory Hepatoblastoma After Chemotherapy

NCT05024331CompletedPrimary

A Prediction Model of Hematological Recovery After High-dose Chemotherapy in Pediatric Solid Tumor

NCT02564198Phase 1CompletedPrimary

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

NCT04944875Not ApplicableCompletedPrimary

Effects of Music and Maternal Voice on Sedation Depth and Sedative Use During Pediatric Magnetic Resonance Imaging.

NCT03222258Completed

Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients

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