NCT05016154

Brief Summary

The aim is to assess the effectiveness of online group CBT for reducing symptoms of depression and anxiety among university students. The investigators will conduct a four-arm randomised control trial comparing a 10-session online group CBT intervention to three mental health apps (namely SilverCloud guided, SilverCloud unguided, and Mood Flow).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
400

participants targeted

Target at P75+ for not_applicable depression

Timeline
Completed

Started Jul 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 26, 2021

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

August 4, 2021

Completed
19 days until next milestone

First Posted

Study publicly available on registry

August 23, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

August 23, 2021

Status Verified

August 1, 2021

Enrollment Period

10 months

First QC Date

August 4, 2021

Last Update Submit

August 17, 2021

Conditions

Keywords

online group psychological interventiondepressionanxietyonline group Cognitive Behavioural TherapyApp-based interventionsRandomized controlled trial

Outcome Measures

Primary Outcomes (2)

  • Change from baseline scores in the mean symptoms of depression as measured by the PHQ-9 at 3-months.

    Determine if a 10-week online group CBT (GCBT) intervention effectively reduces mean scores of depression, between baseline and 3-month follow up, among university students when compared with three control group interventions (i.e., Mood Flow, SilverCloud guided, and SilverCloud unguided).

    Baseline and 3-month follow up assessment for experiment and control interventions groups.

  • Change from baseline scores in the mean symptoms of anxiety as measured by the GAD-7 at 3-months.

    Determine if a 10-week online group CBT (GCBT) intervention effectively reduces mean scores of anxiety, between baseline and 3-month follow up, among university students when compared with three control group interventions (i.e., Mood Flow, SilverCloud guided, and SilverCloud unguided).

    Baseline and 3-month follow up assessment for experiment and control interventions groups.

Study Arms (4)

Online group CBT intervention

EXPERIMENTAL

Online group CBT delivered via Microsoft Teams (a secure web-based video conferencing platform) in 10 weekly workshops of 60-75 minutes.

Behavioral: Online Group CBT intervention

SilverCloud guided

ACTIVE COMPARATOR

The SilverCloud app is a set of programs and courses that can be completed on a phone, tablet or computer. Students are also contacted by the SilverCloud support team which offers them guidance and support while using the app. Silvercloud uses principles borrowed from both a popular type of counseling called Cognitive Behavioral Therapy (CBT) and Mindfulness. Each module takes approximately 40minutes to complete. Students are encouraged to complete at least one module per week.

Behavioral: SilverCloud guided

SilverCloud unguided

ACTIVE COMPARATOR

The SilverCloud app is a set of programs and courses that can be completed on a phone, tablet or computer. Students are encouraged to use the app as they see fit, although guidelines to using the app are provided. Silvercloud uses principles borrowed from both a popular type of counseling called Cognitive Behavioral Therapy (CBT) and Mindfulness. Each module takes approximately 40minutes to complete. Students are encouraged to complete at least one module per week.

Behavioral: SilverCloud Unguided

Mood Flow

ACTIVE COMPARATOR

The Moodflow app is a mood tracker and journal that helps students figure out what changes their mood. Students are encouraged to use the app as they see fit, although guidelines to using the app are provided.

Behavioral: Mood Flow

Interventions

Group of participants complete 10 weeks of Online Group CBT intervention

Online group CBT intervention

Group of participants make use of the SilverCloud guided app

SilverCloud guided

Group of participants make use of the SilverCloud Unguided app

SilverCloud unguided
Mood FlowBEHAVIORAL

Group of participants make use of the Mood Flow app

Mood Flow

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18 or older years.
  • Enrolled as a student at Stellenbosch University.
  • Provide Informed Consent.
  • Access to internet to join the online group.

You may not qualify if:

  • No internet availability.
  • Did not provide Informed Consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stellenbosch University

Cape Town, Western Cape, 7550, South Africa

RECRUITING

Related Publications (1)

  • Bantjes J, Kazdin AE, Cuijpers P, Breet E, Dunn-Coetzee M, Davids C, Stein DJ, Kessler RC. A Web-Based Group Cognitive Behavioral Therapy Intervention for Symptoms of Anxiety and Depression Among University Students: Open-Label, Pragmatic Trial. JMIR Ment Health. 2021 May 27;8(5):e27400. doi: 10.2196/27400.

    PMID: 34042598BACKGROUND

MeSH Terms

Conditions

DepressionAnxiety Disorders

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorMental Disorders

Study Officials

  • Jason Bantjes, PhD

    University of Stellenbosch

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Elsie Breet, PhD

CONTACT

Jason Bantjes, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 4, 2021

First Posted

August 23, 2021

Study Start

July 26, 2021

Primary Completion

June 1, 2022

Study Completion

December 1, 2022

Last Updated

August 23, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations