NCT05012163

Brief Summary

In the current study, the study team will explore whether small incentives are effective at promoting flu vaccine uptake. The study is designed to compare the relative efficacy of incentives of equal perceived expected value (EV) or equal implementation costs, to assess whether people are more likely to get vaccinated in response to lotteries with very high payoffs than to small certain cash payout or slightly higher-probability, more moderate payoffs. In particular, given the potential appeal of official state lottery tickets, one study arm will receive a Pennsylvania scratch-off lottery ticket for getting a flu vaccine. A primary hypothesis is that lotteries will outperform simple reminders (encouraging respondents to get the flu shot at their upcoming appointment) and the standard of care, representing the ambient healthcare system and public health campaigns to increase vaccination.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57,581

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 4, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 19, 2021

Completed
16 days until next milestone

Study Start

First participant enrolled

September 4, 2021

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
1 month until next milestone

Results Posted

Study results publicly available

February 13, 2023

Completed
Last Updated

December 30, 2024

Status Verified

December 1, 2024

Enrollment Period

4 months

First QC Date

August 4, 2021

Results QC Date

December 21, 2022

Last Update Submit

December 13, 2024

Conditions

Keywords

LotteryFinancial Incentives

Outcome Measures

Primary Outcomes (1)

  • Flu Vaccination at Appointment

    Received flu vaccination at relevant PCP or specialty appointment.

    3 days after patient is randomized

Secondary Outcomes (3)

  • Flu Vaccination Within 7 Days

    Within 7 days of when patient is randomized

  • Flu Diagnosis

    During the 2021-22 flu season (Up to 8 months, from the time the patient is randomized through April 30, 2022)

  • Flu Complications

    During the 2021-22 flu season (Up to 11 months, from the time the patient is randomized through July 31, 2022)

Other Outcomes (4)

  • Flu Vaccination (Among Subject Cohabitants) Within 28 Days

    Within 28 days of when the study subject is randomized

  • Flu Vaccination at Appointment by Gender

    3 days after the patient is randomized.

  • Flu Vaccination at Appointment by Race

    3 days after the patient is randomized.

  • +1 more other outcomes

Study Arms (4)

Pennsylvania (PA) Lottery Scratch-Off Financial Incentive

EXPERIMENTAL

Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds

Behavioral: ReminderBehavioral: Financial incentiveBehavioral: Lottery

Certain Cash Payout Financial Incentive

EXPERIMENTAL

Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment.

Behavioral: ReminderBehavioral: Financial incentive

Reminder / Active Control (No Financial Incentive)

EXPERIMENTAL

Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot.

Behavioral: Reminder

No Treatment Control

NO INTERVENTION

No additional contact beyond standard Geisinger flu shot communications

Interventions

ReminderBEHAVIORAL

Letter, short message service (SMS) text, phone, and/or email

Certain Cash Payout Financial IncentivePennsylvania (PA) Lottery Scratch-Off Financial IncentiveReminder / Active Control (No Financial Incentive)

Letter, SMS, phone, and/or email

Certain Cash Payout Financial IncentivePennsylvania (PA) Lottery Scratch-Off Financial Incentive
LotteryBEHAVIORAL

Letter, SMS, phone, and/or email

Pennsylvania (PA) Lottery Scratch-Off Financial Incentive

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18+
  • Pennsylvania mailing address listed
  • Geisinger primary care provider (PCP) assigned
  • Upcoming appointment with PCP or select specialist who stocks and can administer the vaccine during the study period

You may not qualify if:

  • Has opted out of receiving messages from Geisinger on all modalities being tested

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Geisinger Clinic

Danville, Pennsylvania, 17822, United States

Location

MeSH Terms

Conditions

Influenza, HumanHealth Behavior

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsOrthomyxoviridae InfectionsRNA Virus InfectionsVirus DiseasesRespiratory Tract DiseasesBehavior

Results Point of Contact

Title
Gail Rosenbaum
Organization
Geisinger

Study Officials

  • Michelle N Meyer, PhD JD

    Geisinger Clinic

    PRINCIPAL INVESTIGATOR
  • Christopher F Chabris, PhD

    Geisinger Clinic

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Masking Details
Providers who prescribe vaccination and diagnose conditions will not be randomized to study arms or informed of patient assignment. Although patients will not be explicitly informed of which arm they were randomized to, they will be aware of the messages they receive.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Eligible patients will be randomly assigned to one of four arms: * Pennsylvania Lottery Scratch-Off Financial Incentive * Certain Cash Payout Financial Incentive * Reminder / Active Control Arm (No Financial Incentive) * No Treatment Control Arm
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 4, 2021

First Posted

August 19, 2021

Study Start

September 4, 2021

Primary Completion

December 31, 2021

Study Completion

December 31, 2022

Last Updated

December 30, 2024

Results First Posted

February 13, 2023

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will share

Data with no personally identifiable information will be made available to other researchers on the Open Science Framework for transparency. This will include the essential data and code needed to replicate the analysis that yielded reported findings.

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE
Time Frame
By the paper's online publication date or within 12 months of the primary completion date (whichever comes first). Data will remain available for as long as the Open Science Framework hosts it.
Access Criteria
The data on the Open Science Framework will be open to anyone requesting that information.
More information

Locations