A Mobile Phone Intervention to Promote Adherence to Survivorship Care Among Adolescent and Young Adult Cancer Survivors

NCT05000359 | Withdrawn Early Phase 1

• 1 other identifier: 21-000440
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Adolescents and young adults (AYA) survivors of childhood cancer receive inadequate surveillance for treatment-related late effects. This study evaluates the acceptability and feasibility of a mobile phone messaging intervention targeting behavior changes related to receiving survivorship care among AYA survivors. Content from an existing text-messaging survivorship education intervention will be adapted to a novel text-messaging platform, Chorus. Ten AYA survivors will be recruited to participate in the expanded 12-week text messaging intervention. In-depth interviews will be conducted with each participant during the study, and a focus group with all participants will be conducted at the end of the study. Qualitative analysis will determine areas for improvement in the text messaging intervention in order to ensure acceptability and feasibility in AYA survivors. The text messaging intervention on Chorus will be adapted to better suit the needs of AYA survivors based on the results of the qualitative analysis. Mobile phone interventions offer a cost-effective, age-appropriate approach to AYA survivorship care education. If effective, the text-messaging intervention will be evaluated in a randomized, controlled pilot trial to improve rates of survivorship care and clinical outcomes for AYA survivors.

Conditions

Survivors of Childhood Cancer

Outcome Measures

Primary Outcomes (1)

• Mobil Phone Muti-Media messaging

  Acceptability and feasibility of an expanded mobile phone intervention as assessed by key informant interview questions and a focus group discussion developed based on the Technology Acceptance Model: (a) perceived usefulness of the text messaging system for completing ASAP goals, (b) perceived ease of use of the text messaging system for completing ASAP goals, and (c) effect of the text messaging system on intent to complete ASAP goals. The assessment will be qualitative only. The Technology Acceptance Model (TAM) evaluates how likely a user of new technology will accept and continue to use the new technology. TAM posits that if the technology is perceived as useful, easy to use, and increases intent to use - then the technology is more likely to be accepted. Interview questions and focus group discussion points will ask about these criteria. If responses satisfy the TAM criteria, this supports mobile phone intervention as acceptable and feasible for use in AYA cancer survivors.

  one month

Secondary Outcomes (2)

• Key Informant Interview regarding risk for late effects due to prior cancer treatment and intent to seek survivorship care.

  up to 1 year

• Key Informant Interview to identify themes from which the mobile phone intervention will be refined in order to improve its potential impact on the completion of participants' Adolescent and Young Adult Survivorship Action Plan (ASAP) goals.

  up to 1 year

Study Arms (1)

AYA Text messaging intervention

OTHER

Ten AYA survivors will be recruited to participate in the expanded 12-week text messaging intervention.

Behavioral: text messaging intervention

Interventions

text messaging intervention BEHAVIORAL

Ten AYA survivors will be recruited to participate in the expanded 12-week text messaging intervention.

AYA Text messaging intervention

Eligibility Criteria

• Age: 18 Years - 39 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients must be between the ages of 18 to 39 years at the time of enrollment
• Patient must reside in the greater Los Angeles area.
• Patients must have received survivorship care at the University of California at Los Angeles (UCLA)
• Patients must be fluent in English.
• Patients must be off cancer therapy for at least one year.
• Patients must have personal access to a smart phone with text messaging and internet and/or data capability.

Sponsors & Collaborators

• Jonsson Comprehensive Cancer Center: lead

Study Sites (1)

University of California at Los Angeles

Los Angeles, California, 90095, United States

Location

Study Officials

• Mark C Garcia, MD

  University of California, Los Angeles

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Ten AYA survivors will be recruited to participate in the expanded 12-week text messaging intervention.

Study Record Dates

• First Submitted: July 9, 2021
• First Posted: August 11, 2021
• Study Start: July 12, 2021
• Primary Completion: July 3, 2023
• Study Completion: July 3, 2023
• Last Updated: July 12, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)