MST in Patients With Inflammatory Rheumatic Disease

NCT04998955 | Completed

• 1 other identifier: HHRevma2 - MST
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the feasibility of 10 weeks of maximal strength training (MST) in patients with inflammatory rheumatic disease. As well as the effects of MST on maximal strength, rate of force developement and quality of life in this patient population.

Conditions

Inflammatory Rheumatism

Keywords

Maximal strength; Quality of life; Heavy resistance training; Rate of force development; Rehabilitation

Outcome Measures

Primary Outcomes (1)

• Change in physiological measure assesed in the horizontal leg press apparatus

  Maximal strength; one repetition maximum (measured in kg)

  At baseline and after 10 weeks.

Secondary Outcomes (1)

• Change in health-related quality of life assessed by Norwegian RAND-36

  At baseline and after 10 weeks

Study Arms (2)

MST group

EXPERIMENTAL

Exercise intervention, 20 supervised MST sessions

Behavioral: Maximal strength training

Control group

NO INTERVENTION

IRD patient controls

Interventions

Maximal strength training BEHAVIORAL

Exercise intervention utilizing 4 x 4 repetitions heavy resistance training

MST group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Inflammatory rheumatic disease

You may not qualify if:

• Inability to complete the testing procedures
• Pregnancy
• Not able to perform exercise intervention
• Planed surgeries or other plans during initial exercise intervention period than directly will effect the testing or training.
• unstable ischemic heart disease
• unstable aortic stenosis or aneurysm
• Less than 80% compliance of planned training sessions

Sponsors & Collaborators

• Molde University College: lead

Study Sites (1)

Myworkout - Medical Rehabilitation Clinic

Trondheim, Please Select, 7047, Norway

Location

Related Publications (1)

• Haglo H, Berg OK, Hoff J, Helgerud J, Wang E. Maximal strength training in patients with inflammatory rheumatic disease: implications for physical function and quality of life. Eur J Appl Physiol. 2022 Jul;122(7):1671-1681. doi: 10.1007/s00421-022-04948-w. Epub 2022 Apr 19.

  PMID: 35438424 DERIVED

MeSH Terms

Conditions

Rheumatic Fever

Condition Hierarchy (Ancestors)

Streptococcal Infections; Gram-Positive Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases

Study Officials

• Jan Helgerud, PhD

  Norwegian University of Science and Technology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: The outcome assessor was blinded with regards to which intervention group the participants had been assigned.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized controlled trial

Study Record Dates

• First Submitted: July 12, 2021
• First Posted: August 10, 2021
• Study Start: October 1, 2018
• Primary Completion: December 21, 2018
• Study Completion: December 21, 2018
• Last Updated: August 10, 2021

Record last verified: 2021-08

Locations

NO (1)