Sex Determination From Scapula Using 3-D Computed Tomography in Sample of Sohag Governorate Population

NCT04991610 | Unknown

• 1 other identifier: Soh-Med-21-07-15
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

One of the most difficult areas of forensic science is identifying individuals. Accurate sex estimation based on measurements of dimorphic dimensions in unknown human remains is a crucial first step toward making individual identification. the most accurate approach to determine sex by bone size is based on os coxae or skull. After natural disaster their presence can never be guaranteed, therefore the development of methods of sex determination using other skeletal elements is crucial. The scapula is a paired short bone that will be researched in this study. The decision to focus on the scapula was made in the first place because of its minor morphological alterations after growing is complete. Second, short and flat bones appear to be better maintained than lengthy bones, which are frequently fractured, scattered, and mixed together. Scapular muscle attachments provide protection to the bone making it difficult to fracture or break . Comparative studies on different populations have shown population-specific results in the discriminant function equations for sex estimation. There is significant population variation due to sexual dimorphism in the growth rate and developmental process of human beings. Genetics play an important role in this variation. Nevertheless, environmental factors, nutrition, secular changes and diseases also play an important role in sexual dimorphism .

Conditions

Sex Discrimination

Outcome Measures

Primary Outcomes (3)

• Maximum scapular length

  the parameter measured The length between the highest point of superior angle and lowest point of inferior angle via software program . All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

  12 Months

• Scapular breadth

  the parameter measured from the middle of the dorsal border of glenoid fossa to the end of spinal axis on the vertebral border. via software program All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

  12 Months

• Maximum length of spine

  the parameter measured From the medial border of the scapula at the spinous axis to the most lateral point on the scapular spine via software program . All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

  12 Months

Study Arms (2)

Adult male

ACTIVE COMPARATOR

CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

Radiation: computed tomography

Adult female

ACTIVE COMPARATOR

CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

Radiation: computed tomography

Interventions

computed tomography RADIATION

CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

Adult female; Adult male

Eligibility Criteria

• Age: 25 Years+
• Gender Eligibility Details: shoud be above 25 years and be healthy.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• persons above 25 years old

You may not qualify if:

• Cases below 25 years
• scapular, vertebral fractures
• growth disorders
• severe osteoporosis
• tumor
• arthritis
• previous orthopedic surgery
• infection

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university

Sohag, Egypt

RECRUITING

Related Publications (3)

• O'Bright L, Peckmann TR, Meek S. Is "Latin American" population-specific? Testing sex discriminant functions from the Mexican tibia on a Chilean sample. Forensic Sci Int. 2018 Jun;287:223.e1-223.e7. doi: 10.1016/j.forsciint.2018.03.046. Epub 2018 Apr 4.

  PMID: 29692330 BACKGROUND

• Ubelaker DH, DeGaglia CM. Population variation in skeletal sexual dimorphism. Forensic Sci Int. 2017 Sep;278:407.e1-407.e7. doi: 10.1016/j.forsciint.2017.06.012. Epub 2017 Jun 19.

  PMID: 28698063 BACKGROUND

• Papaioannou VA, Kranioti EF, Joveneaux P, Nathena D, Michalodimitrakis M. Corrigendum to "Sexual dimorphism of the scapula and the clavicle in a contemporary Greek population: Applications in forensic identification" [Forensic Sci. Int. 217 (2012) 231.e1-231.e7]. Forensic Sci Int. 2017 Jan;270:183. doi: 10.1016/j.forsciint.2016.12.012. Epub 2016 Dec 16. No abstract available.

  PMID: 27992821 BACKGROUND

MeSH Terms

Conditions

Sexism

Condition Hierarchy (Ancestors)

Prejudice; Social Behavior; Behavior; Social Discrimination

Study Officials

• maha A Helal, professor

  faculty of medicine sohag university

  STUDY DIRECTOR

Central Study Contacts

Dalia M Khalaf, demonstrator

CONTACT

01050116734; dalia011081@med.sohag.edu.eg

Maha A Helal, Professor

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Teaching Assistant, Department of Forensic Medicine and Toxicology

Model Details: All measurements will be made by scanning of patients who coming to radiology department at sohag university hospital known of their birth date and sex who underwent thoracic CT scan evaluation during a pulmonary screening program . a descriptive comparative study will be conducted on total population of 100 sohag subjects (50 adult males and 50 adult females) from 25 years and above , using CT scan images to estimate the above mentioned diameters..

Study Record Dates

• First Submitted: July 25, 2021
• First Posted: August 5, 2021
• Study Start: July 1, 2021
• Primary Completion: July 1, 2022
• Study Completion: July 1, 2022
• Last Updated: August 5, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: in july 2023
• Access Criteria: Data will be gathered and analyzed using the mean, mode, and standard deviation by using SPSS program to compare mean differences between the sexes. The statistical difference will be done to compare two groups of parametric data by student - t-test .

Locations

EG (1)