Success Metrics

Clinical Success Rate
75.1%

Based on 160 completed trials

Completion Rate
75%(160/213)
Active Trials
674(63%)
Results Posted
101%(162 trials)
Terminated
53(5%)

Phase Distribution

Ph not_applicable
110
10%
Ph phase_2
455
43%
Ph phase_1
281
26%
Ph phase_3
105
10%
Ph phase_4
4
0%
Ph early_phase_1
40
4%

Phase Distribution

321

Early Stage

455

Mid Stage

109

Late Stage

Phase Distribution995 total trials
Early Phase 1First-in-human
40(4.0%)
Phase 1Safety & dosage
281(28.2%)
Phase 2Efficacy & side effects
455(45.7%)
Phase 3Large-scale testing
105(10.6%)
Phase 4Post-market surveillance
4(0.4%)
N/ANon-phased studies
110(11.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

60.8%

160 of 263 finished

Non-Completion Rate

39.2%

103 ended early

Currently Active

674

trials recruiting

Total Trials

1,062

all time

Status Distribution
Active(741)
Completed(160)
Terminated(103)
Other(58)

Detailed Status

Recruiting407
Active, not recruiting267
Completed160
Not yet recruiting66
Terminated53
Withdrawn50

Development Timeline

Analytics

Development Status

Total Trials
1062
Active
674
Success Rate
75.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 140 (4.0%)
Phase 1281 (28.2%)
Phase 2455 (45.7%)
Phase 3105 (10.6%)
Phase 44 (0.4%)
N/A110 (11.1%)

Trials by Status

recruiting40738%
not_yet_recruiting666%
terminated535%
suspended262%
active_not_recruiting26725%
completed16015%
enrolling_by_invitation10%
unknown323%
withdrawn505%

Recent Activity

Clinical Trials (1,062)

Showing 20 of 1,062 trialsScroll for more
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT03244384Phase 3

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Active Not Recruiting
NCT07198074Phase 3

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Recruiting
NCT05828069Phase 2

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recruiting
NCT07645469Phase 1

FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

Not Yet Recruiting
NCT05904080Phase 2

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Recruiting
NCT03606967Phase 2

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Recruiting
NCT05112601Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT06630416Phase 2

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

Recruiting
NCT05226663Phase 2

A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer

Active Not Recruiting
NCT04181060Phase 3

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting
NCT05058651Phase 2

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Recruiting
NCT05896839Phase 1

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Recruiting
NCT05092958Phase 3

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

Active Not Recruiting
NCT04214249Phase 2

BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT01810913Phase 2

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Recruiting
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Recruiting
NCT07645651Phase 1

Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic Cancer

Not Yet Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
1,062