NCT04989933

Brief Summary

The erector spine plane block is currently used in many surgeries to provide postoperative analgesia. It has also been used successfully in open-heart surgery for postoperative sternotomy pain. However, an ideal volume that will provide optimum analgesia has not yet been determined. This study aims to compare the effects of ESP block administered in two different volumes on poststernotomy pain.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 31, 2021

Completed
2 days until next milestone

Study Start

First participant enrolled

August 2, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 4, 2021

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2021

Completed
Last Updated

August 4, 2021

Status Verified

July 1, 2021

Enrollment Period

3 months

First QC Date

July 31, 2021

Last Update Submit

July 31, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rescue analgesia

    Total amount of rescue analgesic

    Post-extubation 24 hours

Study Arms (2)

ESP 20 ml

ACTIVE COMPARATOR

Ultrasound-Guided erector spinae plane block with 20 ml of 0.25% bupivacaine

Procedure: Ultrasound-guided erector spinae plane block

ESP 30 ml

ACTIVE COMPARATOR

Ultrasound-Guided erector spinae plane block with 30 ml of 0.25% bupivacaine

Procedure: Ultrasound-guided erector spinae plane block

Interventions

Ultrasound-Guided erector spinae plane block with 0.25% bupivacaine

ESP 20 mlESP 30 ml

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • American Society of Anesthesiologist's physiologic state I-III patients Undergoing Open Heart Surgery

You may not qualify if:

  • chronic pain bleeding disorders renal or hepatic insufficiency patients on chronic non-steroidal anti-inflammatory medications emergency cases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assoc. Prof.

Study Record Dates

First Submitted

July 31, 2021

First Posted

August 4, 2021

Study Start

August 2, 2021

Primary Completion

November 1, 2021

Study Completion

November 1, 2021

Last Updated

August 4, 2021

Record last verified: 2021-07