Respiratory Muscle Activations During Stable Threshold Load and Increasing Threshold Load Endurance Tests in COPD

NCT04983485 | Unknown

• 1 other identifier: AIBU-FTR-CT-02
• Study Type: observational
• Target: 21
• Locations: 0 countries
• Sites: N/A

Brief Summary

In the literature, it has been observed that there is an increase in respiratory muscle activity in individuals with COPD due to the increase in respiratory workload and in response to the loads given by respiratory muscle training devices. However, no study has been found in the literature comparing the activation of respiratory muscles during constant threshold load endurance test and increasing threshold load endurance test performed with respiratory muscle training devices, which are important for respiratory muscle function evaluation. With this planned study, it is aimed to contribute to the literature by examining the changes in muscle activation during the constant threshold load and increasing threshold load endurance tests where different workloads are given and by comparing these changes.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

Chronic Obstructive Pulmonary Disease; Surface Electromyography; Ventilation; Respiratory Endurance Test

Outcome Measures

Primary Outcomes (1)

• Surface Electromyography

  Activation of respiratory muscles will be performed with a surface Electromyography (EMG) device. The measurement will be performed by placing Electromyography (EMG) electrodes on the motor points of the respiratory muscles. Increased respiratory muscle activations indicate that respiratory muscles are used more; The decrease in respiratory muscle activations indicates that the respiratory muscles are used less.

  45 minutes

Secondary Outcomes (7)

• Incremental Threshold Load Endurance Test

  10 minutes

• Sustained Threshold Load Endurance Test

  10 minutes

• Pulmonary Function Test:

  5 minutes

• Measurement of Maximal Inspiratory Pressure

  5 minutes

• Chronic Obstructive Pulmonary Disease Assessment Test

  2 minutes

Study Arms (1)

Observational Group

Individuals who were diagnosed with COPD by Bolu Abant İzzet Baysal University Medical Faculty Chest Diseases Department and referred to Bolu Abant İzzet Baysal University Health Sciences Faculty Physiotherapy and Rehabilitation Department will be included in the study.

Other: Observational

Interventions

Observational OTHER

Respiratory muscle electromyographic activations of individuals will be evaluated during the test while breathing rapidly and deeply from the beginning of the constant threshold load endurance test and the increasing threshold load endurance test until the end of the test, and at rest. Respiratory muscle endurance will be evaluated with constant threshold load endurance test and increasing threshold load endurance test, respiratory functions with pulmonary function test, respiratory muscle strength with intraoral pressure measurement device, health condition disorder with Chronic Obstructive Pulmonary Disease Assessment Scale, dyspnea with Modified Medical Research Council Dyspnea Scale and Modified Borg Scale. Participants' names, anthropometric measurements, demographic data, contact information and medical history will be collected and recorded with the patient anamnesis form.

Observational Group

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Chronic obstructive pulmonary disease (COPD) is a common, preventable and treatable disease characterized by persistent respiratory symptoms and airway limitation due to airway and/or alveolar abnormality resulting from exposure to harmful gases or particles and many factors that cause abnormal lung development.

You may qualify if:

• Individuals diagnosed with chronic obstructive pulmonary disease
• Be between the ages of 40-65
• No medication changes due to acute exacerbation for at least three weeks
• Be stable
• Volunteering to participate in research
• To cooperate
• Patients with written consent form
• Healthy individuals in a similar age range without a diagnosed disease and symptoms will be included

You may not qualify if:

• Those with a history of chronic obstructive pulmonary disease exacerbations
• Individuals with orthopedic disease
• Individuals with neurological disease
• Individuals with other co-existing lung and systemic diseases other than chronic obstructive pulmonary disease
• Those who have had major surgery in the past few months
• Individuals with a history of recurrent significant clinical infections
• Have cognitive problems
• Having had unstable angina,
• Previous Myocardial Infarction
• Individuals with severe congestive heart failure refractory to medical therapy, individuals with uncontrolled hypertension
• Individuals with cancer

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Aspiration

Interventions

Watchful Waiting

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders

Intervention Hierarchy (Ancestors)

Outcome Assessment, Health Care; Outcome and Process Assessment, Health Care; Quality of Health Care; Health Services Administration

Central Study Contacts

Eylem TÜTÜN YÜMİN, Assoc Prof.

CONTACT

05056763191; eylemtutun78@hotmail.com

Ceyhun TOPCUOĞLU, Res. Assist.

CONTACT

05356535137; ceyhuntopcuoglu1@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: July 9, 2021
• First Posted: July 30, 2021
• Study Start: June 25, 2023
• Primary Completion: July 25, 2023
• Study Completion: August 25, 2023
• Last Updated: October 28, 2022

Record last verified: 2022-10

Data Sharing

• IPD Sharing: Will not share