NCT04983316

Terminated

TPF Machine Learning Algorithms

Universitaire Ziekenhuizen KU Leuven Source

Universitaire Ziekenhuizen KU Leuven

ClinicalTrials.gov

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Other study identifiers

Sponsor study identifier

S64352

Study Type

observational

Actual enrollment (reported)

70

Locations

1 country

Sites

1

Timeline

Study Start

October 5, 2020

Actual (reported)

Primary Completion

June 27, 2023

Actual (reported)

Study Completion

December 6, 2024

Actual (reported)

Brief Summary

To adopt a machine learning technique to decide whether operative or non-operative treatment will result in the best patient-outcome.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: terminated
Actual enrollment (reported): 70 participants
Study completion date: December 6, 2024
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
October 5, 2020
Actual (reported)
First Submitted
July 16, 2021
Actual (reported)
First Posted
July 30, 2021
Actual (reported)
Primary Completion
June 27, 2023
Actual (reported)
Study Completion
December 6, 2024
Actual (reported)

Last Updated: July 29, 2025
Status Verified: July 2025
Last Update Submitted: July 25, 2025

Conditions

Tibial Plateau Fracture

Outcome Measures

Primary Outcomes (1)

Machine learning algorithm
To identify the most suitable machine learning algorithm that predicts the best treatment for future patients. The prediction will be improved over time by additional input.
1 year

Secondary Outcomes (2)

Clinical factors
1 year
Radiological factors
1 year

Eligibility Criteria

Age18 Years+

Sexall

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients of UZ Leuven

You may qualify if:

Age \> 18 years
Proximal tibia plateau fracture

Sponsors & Collaborators

Universitaire Ziekenhuizen KU Leuven
Otherlead

Study Sites (1)

UZ Leuven

Leuven, Vlaams-Brabant, 3000, Belgium

MeSH Terms

Conditions

Tibial Plateau Fractures

Condition Hierarchy (Ancestors)

Knee FracturesFractures, BoneWounds and InjuriesTibial FracturesKnee InjuriesLeg Injuries

Study Officials

Harm Hoekstra, Prof. MD
UZ Leuven
PRINCIPAL INVESTIGATOR

Enrollment

70 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Prof. dr. Harm Hoekstra

Study Record Dates

First Submitted

July 16, 2021

First Posted

July 30, 2021

Study Start

October 5, 2020

Actual (reported)

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Phase 1Recruiting

NCT06474949

Local Anesthetic for Plateau Fractures

Phase 4Not Yet Recruiting

NCT07251699

EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES

Not ApplicableEnrolling By Invitation

NCT06918171

Clinical Efficacy of Open Reduction and Suture Bridge Fixation for PCL Tibial Avulsion Fractures

Not ApplicableCompleted

NCT07773402

Comparison of Functional Outcome Between Locking Plate Technique Versus Hybrid Ilizarov Technique in Patients With Schatzker Type V and VI Tibial Plateau Fractures

Not ApplicableRecruiting

NCT06931366

Posterior Column Fractures of Tibial Plateau

Not Yet Recruiting

Patient is able to attend follow-up visits

You may not qualify if:

Age \< 18 years
Bilateral fractures
Neurologic disorders (ie paraplegia, CVA, dementia etc.)
Not understanding Dutch or English

Contact the study team to confirm eligibility.

Primary Completion

June 27, 2023

Actual (reported)

Study Completion

December 6, 2024

Actual (reported)

Last Updated

July 29, 2025

Record last verified: 2025-07

Source record

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Source: ClinicalTrials.gov.

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Registry identifier: NCT04983316
Data provider: ClinicalTrials.gov
Source updated: 2025-07-29
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:40:08 UTC

Locations

BE(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations