NCT04981249

Brief Summary

The aim of the study was to analyze the patterns of chronic multimorbidity of a cohort of Covid-19 patients, and to assess the relation between the patterns and the development of severe infection or mortality.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14,286

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2021

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2021

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2021

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

July 27, 2021

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 28, 2021

Completed
Last Updated

August 4, 2021

Status Verified

July 1, 2021

Enrollment Period

1 month

First QC Date

July 27, 2021

Last Update Submit

July 28, 2021

Conditions

Keywords

MultimorbidityCluster analysisCovid-19

Outcome Measures

Primary Outcomes (2)

  • Covid-19 severe infection

    Severe COVID-19 infection was defined as the occurrence of at least one of the following conditions during any of the registered COVID-19 episodes: severe respiratory affection (including insufficiency, failure, or distress); use of respiratory support (including mechanical ventilation or oxygen therapy); septic shock; multiple organ failure (the combination of respiratory failure and any other organ failure); inflammatory response; admission to intensive care unit; and mortality.

    From 27-February-2020 to 15-June-2020

  • Covid-19 mortality

    Death associated to COVID-19 infection episode

    From 27-February-2020 to 15-June-2020

Eligibility Criteria

Age21 Years - 95 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Confirmed or suspected Covid-19 patients from the first wave of the pandemic, aged \>20 years, residing in a healthcare region of about 400.000 inhabitants in a Northeast region of Spain (Vallès Occidental Est, Catalonia, Spain).

You may qualify if:

  • Positive results of Covid-19 laboratory tests
  • Covid-19 related clinical profile verified by healthcare professionals

You may not qualify if:

  • Male \>90 years
  • Females \>95 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Corporacio Parc Taulí

Sabadell, 08208, Spain

Location

Related Publications (1)

  • Lleal M, Corral-Vazquez C, Bare M, Comet R, Herranz S, Baigorri F, Gimeno-Miguel A, Raurich M, Fortia C, Navarro M, Poblador-Plou B, Bare M. Multimorbidity patterns in COVID-19 patients and their relationship with infection severity: MRisk-COVID study. PLoS One. 2023 Aug 31;18(8):e0290969. doi: 10.1371/journal.pone.0290969. eCollection 2023.

Related Links

MeSH Terms

Conditions

COVID-19Chronic Disease

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Coordinator

Study Record Dates

First Submitted

July 27, 2021

First Posted

July 28, 2021

Study Start

January 1, 2021

Primary Completion

January 31, 2021

Study Completion

May 31, 2021

Last Updated

August 4, 2021

Record last verified: 2021-07

Locations