NCT04976166

Brief Summary

Shared decision making (SDM) is an approach where clinicians and patients make decisions together using the best available evidence. An understanding of the patient's treatment goals, the advantages and disadvantages of treatment options, and the likelihood of achieving the outcomes are important to patients. International guidelines recommend that all patients with chronic kidney disease (CKD) at pre-dialysis stage should be educated to improve their knowledge and understanding of their condition and to choose the options for renal replacement therapy (RRT). Despite these recommendations, pre-dialysis educations are often infrequent. Many patients feel unprepared. Wrong or insufficient understanding due to insufficient explanation of treatment can lead to negative emotions. This may lead to a situation in which the patient loses the opportunity to make patient's own choices, resulting in emergency dialysis or dialysis modality that is not suitable for patients. Therefore, this study aims to evaluate whether SDM has an effect on the choice of RRT among CKD patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,194

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

19 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 26, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 21, 2021

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 26, 2021

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

March 25, 2022

Status Verified

March 1, 2022

Enrollment Period

3.8 years

First QC Date

June 21, 2021

Last Update Submit

March 9, 2022

Conditions

Keywords

chronic kidney diseasedialysisshared decision making

Outcome Measures

Primary Outcomes (1)

  • The ratio of hemodialysis to non-hemodialysis

    To compare the proportion of hemodialysis versus non-hemodialysis (peritoneal dialysis and kidney transplantation) treatments among the groups

    12 months

Secondary Outcomes (5)

  • Economic efficiency using a cost-utility analysis

    Month 2, and 12

  • Patients' satisfaction assessed by Patient Satisfaction Questionnaire (ZUF-8)

    Month 0, 2, and 12

  • Patients' evaluation of the SDM process assessed by Shared Decision-Making Questionnaire (SDM-Q-9)

    Month 0, 2, and 12

  • Patients' adherence to medication assessed by Morisky 8-item Medication Adherence Scale (MMAS-8)

    Month 0, 2, and 12

  • unplanned dialysis

    12 months

Study Arms (3)

Conventional group

ACTIVE COMPARATOR

Videos and leaflets will be provided. Patients will have education using leaflets for 5 minutes in each hospital at months 0 and 2, respectively.

Behavioral: Education

Extensive Informed Decision Making group

EXPERIMENTAL

Videos, leaflets, and intensive learning materials will be provided. Patients in the EIDM group will receive more informed and detailed education than those in the conventional group. Patients will have education for more than 10 minutes at months 0 and 2, respectively.

Behavioral: Education

Shared Decision Making group

EXPERIMENTAL

Videos, leaflets, and intensive learning materials will be provided. Patients will check self-assessment items, and then have education according to the patients' preference using a self-developed counseling calendar. Patients will have education for more than 10 minutes at months 0 and 2, respectively.

Behavioral: Education

Interventions

EducationBEHAVIORAL

More informed and detailed education

Extensive Informed Decision Making group

Eligibility Criteria

Age19 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with chronic kidney disease whose nephrologist predicts initiation of renal replacement therapy within 12 months:
  • Patients with grade 5 of chronic kidney disease \[defined as a creatinine-based estimated glomerular filtration rate (eGFR) \< 15 ml/dL/1.73m2 at least 2 times at intervals of 2 weeks or longer\]
  • Patients with the cystatin C-based eGFR \< 15 ml/dL/1.73m2 at least once if the creatinine-based eGFR does not accurately evaluate the kidney function of patient due to patient characteristics
  • Patients whose nephrologist require renal replacement therapy within 12 months due to the patient's comorbidities even when the eGFR is 15ml/dL/1.73m2 or higher
  • Patients aged between 19 and 80 years
  • Patients who understand the study
  • Patients who have no permanent access device for long-term maintenance dialysis

You may not qualify if:

  • Patients who have contraindication to perform peritoneal dialysis due to abdominal surgery
  • Patients whose life expectancy is less than 6 months due to underlying diseases
  • Patients who have enrolled in other clinical trials within 3 months or plan to participate in other clinical trials during this clinical trial period
  • Patients judged by the investigator to be inappropriate for participation in this clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (19)

Bundang Seoul National University Hospital

Seongnam-si, Gyeonggi-do, 13620, South Korea

RECRUITING

Kyungpook National University Chilgok Hospital

Daegu, South Korea

RECRUITING

Kyungpook National University Hospital

Daegu, South Korea

RECRUITING

Daejeon Eulji Medical Center

Daejeon, South Korea

RECRUITING

Dongguk University Ilsan Hospital

Goyang, South Korea

RECRUITING

Chonnam National University Hospital

Gwangju, South Korea

RECRUITING

Gachon University Gil Medical Center

Incheon, South Korea

RECRUITING

Pusan National University Hospital

Pusan, South Korea

RECRUITING

Ewha Woman's University Seoul Hospital

Seoul, South Korea

RECRUITING

Korea University Guro Hospital

Seoul, South Korea

RECRUITING

Kyung Hee University Hospital at Gangdong

Seoul, South Korea

RECRUITING

Samsung Medical Center

Seoul, South Korea

RECRUITING

Seoul National University Boramae Medical Center

Seoul, South Korea

RECRUITING

Seoul National University Hospital

Seoul, South Korea

RECRUITING

Severance Hospital

Seoul, South Korea

RECRUITING

The Catholic University of Korea Eunpyeong St. Mary's Hospital

Seoul, South Korea

RECRUITING

The Catholic University of Korea Seoul St. Mary's Hospital

Seoul, South Korea

RECRUITING

Ulsan University Hospital

Ulsan, South Korea

RECRUITING

Yonsei University Wonju Severance Christian Hospital

Wŏnju, South Korea

RECRUITING

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Study Officials

  • Sejoong Sejoong, MD,PhD

    Seoul National University Bundang Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sejoong Kim, MD,PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 21, 2021

First Posted

July 26, 2021

Study Start

February 26, 2021

Primary Completion

December 1, 2024

Study Completion

December 1, 2024

Last Updated

March 25, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations