Clinical Features and Outcome in Patients With Osseomuscular Type of Wilson's Disease

NCT04965558 | Recruiting

• 1 other identifier: WD-osseomuscular type
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aimed to observe the clinical features and outcome in patients with osseomuscular type of Wilson's disease from a large cohort during long-term follow-up

Conditions

Clinical Features and Outcome

Outcome Measures

Primary Outcomes (2)

• Serum ceruloplasmin

  Serum ceruloplasmin levels were collected among patients with wilson disease. After confirming a non-Gaussian distribution, the reference range of serum ceruloplasmin level was determined.

  From 2004 through 2030

• Urinary Copper Excretion

  The measurement of 24-hour urine copper excretions were collected and measured.

  From 2004 through 2030

Interventions

No intervention OTHER

No intervention

Eligibility Criteria

• Age: 6 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with wilson disease

You may qualify if:

• genetically diagnosed WD patients

You may not qualify if:

• Deny follow-up

Sponsors & Collaborators

• Second Affiliated Hospital, School of Medicine, Zhejiang University: lead

Study Sites (1)

Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310005, China

RECRUITING

Central Study Contacts

Yi Dong

CONTACT

+8618367129345; dongyi720@zju.edu.cn

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 5, 2021
• First Posted: July 16, 2021
• Study Start: January 1, 2004
• Primary Completion: December 1, 2025
• Study Completion (Estimated): January 1, 2030
• Last Updated: July 16, 2021

Record last verified: 2021-07

Locations

CN (1)