Shear Wave Elastography in Diagnosis of Inflammatory and Malignant Pancreatic Diseases

NCT04964648 | Unknown

• 1 other identifier: SW-EG in pancreatic diseases
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Only a few studies that have assessed the normal range value for pancreatic stiffness, inflammatory and malignant pancreatic lesions, shear wave velocities of healthy parenchyma, acute and chronic pancreatitis, malignant lesions of the pancreas will be evaluated and compared with other conventional imaging modalities, and evaluate its role in assessment of severity and prediction of clinical course/ outcome in patients with inflammatory pancreatic diseases.

Conditions

Shear Wave Elastography; Pancreatic Diseases

Keywords

shear wave elastography; pancreatic diseases

Outcome Measures

Primary Outcomes (2)

• shear wave elastography (SWE) in diagnosis of inflammatory and malignant pancreatic diseases

  •To measure the shear wave velocity (displayed in kilopascals (kPa) or meters per second) of inflammatory and malignant pancreatic diseases

  Baseline

• •To compare the diagnostic success rate of shear wave elastography with other conventional imaging modalities

  •To compare the diagnostic success rate of shear wave elastography with those of sonography and computed tomography (CT) for inflammatory and malignant pancreatic diseases.

  Baseline

Study Arms (3)

Inflammatory pancreatic lesions

older than 18 years with a diagnosis of acute or chronic pancreatitis

Device: shear wave elastography

Malignant pancreatic lesions

older than 18 years with a diagnosis of pancreatic neoplasm

Device: shear wave elastography

Control group

Healthy adult subjects

Device: shear wave elastography

Interventions

shear wave elastography DEVICE

Shear wave elastography (SW-EG), a form of ultrasound elastography used in transabdominal ultrasonography, can measure tissue elasticity by generating shear waves inside the organ using the acoustic radiation force impulse (ARFI) The ultrasound machine monitors shear wave propagation and measures the velocity. The shear wave velocity, displayed in kilopascals (kPa) or meters per second

Control group; Inflammatory pancreatic lesions; Malignant pancreatic lesions

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Inflammatory and Malignant pancreatic lesions who will be admitted in Al-Rajhi University Liver Hospital, Assiut, Egypt. * control group: Healthy adult subjects who will be evaluated for annual check-up in Al-Rajhi University Liver Hospital, Assiut, Egypt.

You may qualify if:

• Inflammatory pancreatic lesions (acute or chronic pancreatitis)
• Malignant pancreatic lesions
• Healthy adult control

You may not qualify if:

• Patient with difficult visualization of the pancreas on B-mode sonography.
• Patients with acute liver diseases.
• Obese patient (body mass index \>30 kg/m2).

Sponsors & Collaborators

• Assiut University: lead

Related Publications (31)

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MeSH Terms

Conditions

Pancreatic Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Central Study Contacts

Zeinab Ramadan, Assistant lecturer

CONTACT

01017800673; z.zedan@aun.edu.eg

Zainab Gaber, Assistant professor

CONTACT

01004496692; zainabgaber@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Study Record Dates

• First Submitted: July 3, 2021
• First Posted: July 16, 2021
• Study Start: July 10, 2021
• Primary Completion: July 10, 2022
• Study Completion: July 10, 2023
• Last Updated: July 16, 2021

Record last verified: 2021-07