Efficacy of Jessener Solution Versus Intralesional Steroid in Treatment of Alopecia Areata

NCT04964349 | Unknown Early Phase 1 DMC

• 3 other identifiers: Alazhar faculty of medicineAhmed KadahEman Abd-ellatif
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Alopecia areata is believed to be an autoimmune disease. Treatment primarily relies on intralesional and topical corticosteroids. This study was conducted to evaluate Jessener Solutionas a potential therapeutic modality of Alopecia Areataversusintralesional steroid as regards the efficacy, safety, tolerability, and patients' satisfaction.

Conditions

Alopecia Areata

Outcome Measures

Primary Outcomes (1)

• Effecacy of topical jessener solution in treatment of alopecia areata

  Effecacy of topical jessener solution in treatment of alopecia areata

  6 monthes

Study Arms (2)

Intralesional cortisosteroid injection

EXPERIMENTAL

Intralesional corticosteroid injection

Drug: Corticosteroids Acting Locally

jessener solution

EXPERIMENTAL

topical jessener solution

Drug: Corticosteroids Acting Locally

Interventions

Corticosteroids Acting Locally DRUG

topical application of jessener solution

Also known as: topical jessener solution

Intralesional cortisosteroid injection; jessener solution

Eligibility Criteria

• Age: 12 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Alopecia Areatamultilocuolaris.2.Age from18-50years old. 3.Wash out period is two months. 4.Ophiasis pattern alopecia areata.

You may not qualify if:

• Age less than 12 yearsand more than 40years old. 2.Patient under treatment.3.Patients having another dermatological condition affecting thescalpas eczema.4.Patients with psychiatric disorders.5.Pregnant and lactating females.

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Alazhar faculty of meidicine

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Alopecia Areata

Condition Hierarchy (Ancestors)

Alopecia; Hypotrichosis; Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Ahmed Elshahid, MD

  Alazhar faculty of medicine

  STUDY CHAIR

Central Study Contacts

Ahmed pr Elshahid, MD

CONTACT

00201006262271; ahmedandro@yahoo.com

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor of dermatology, venereology and andrology

Model Details: there are 2 patches of alopecia areata in the same patient one treated with intralesional injection of corticosteroid and the other one will be treated by jessenersolution

Study Record Dates

• First Submitted: July 13, 2021
• First Posted: July 16, 2021
• Study Start: April 21, 2021
• Primary Completion: October 21, 2021
• Study Completion: November 20, 2021
• Last Updated: July 16, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)