Health Effect of Energy Drink Consumption

NCT04961086 | Completed

• 1 other identifier: CHS001
• Study Type: interventional
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

Energy drinks consumption has varied effects on the hemodynamic, blood glucose levels, brain functions and memory. The use of energy drinks is pervasive and especially young adults consume it often as binge drinking. The negative health effects of excessive use of energy drinks has been reported in the scientific literature. Often energy drinks are consumed to enhance alertness and cognition improvement. In this trial, the investigators intend to compare the effects of a widely available energy drink brand in the country with the usual black tea with 5gm sugar and milk. The aims of this study is:

1. 1.To determine the effect of consumption of energy drinks on hemodynamics parameters.
2. 2.To determine the effect of consumption of energy drinks on short term memory
3. 3.To determine the effect of consumption of energy drinks on vigilance in adults
4. 4.To determine the effect of consumption of energy drinks on blood glucose in adults
5. 5.To analyze the effect of energy drink on perception in adults

Conditions

Blood Pressure; Blood Glucose, High; Cognitive Change

Keywords

energy drink; hemodynamics; memory; stroop test

Outcome Measures

Primary Outcomes (4)

• Change in systolic and diastolic blood pressure

  before and after consumption of the energy drink or the tea both systolic and diastolic blood pressures will be measured as per international guidelines for measuring BP

  half hour post consumption

• Change in heart rate

  before and after consumption of the energy drink or the tea heart rate will be measured as per international guidelines

  half hour post consumption

• Change in blood glucose

  before and after consumption of the energy drink or the tea blood glucose levels will be measured as per international guidelines

  half hour post consumption

• Change in short-term memory and vigilance

  before and after consumption of the energy drink or the tea short term memory functions will be measured using color sequence game. We will use STROOP test to assess vigilance

  half hour post consumption

Secondary Outcomes (1)

• perceptions and knowledge of participants about energy drinks

  within one hour of consumption of the energy drink or the active comparator

Study Arms (2)

energy drink arm

EXPERIMENTAL

an open label branded energy drink which contains any one or more of the following ingredients: caffeine, ginseng, taurine

Other: energy drink

tea 5gm sugar arm

ACTIVE COMPARATOR

the usual easily available black tea with sugar 5 grams, and milk

Other: energy drink

Interventions

energy drink OTHER

An easily available 250 ml branded energy drink will be randomized to the partcipants after informed consent. Before and thirty minutes after drinking the given energy drink the participant cognition, heart rate, blood pressure and blood glucose will be measured.

energy drink arm; tea 5gm sugar arm

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Adult volunteers aged between 18-30 years
• Either gender
• Willing to participate

You may not qualify if:

• Known cardiovascular diseases
• Under any medication
• Known Diabetes mellitus or any other chronic disease
• Pregnancy or lactation
• History of neurological disorders
• History of regular alcohol consumption

Sponsors & Collaborators

• Dow University of Health Sciences: lead

Study Sites (1)

Dow University of Health Sciences

Karachi, None Selected, 74200, Pakistan

Location

Related Publications (6)

• Nowak D, Jasionowski A. Analysis of the Consumption of Caffeinated Energy Drinks among Polish Adolescents. Int J Environ Res Public Health. 2015 Jul 10;12(7):7910-21. doi: 10.3390/ijerph120707910.

  PMID: 26184263 RESULT

• Nowak D, Goslinski M, Nowatkowska K. The Effect of Acute Consumption of Energy Drinks on Blood Pressure, Heart Rate and Blood Glucose in the Group of Young Adults. Int J Environ Res Public Health. 2018 Mar 19;15(3):544. doi: 10.3390/ijerph15030544.

  PMID: 29562659 RESULT

• Wesnes KA, Brooker H, Watson AW, Bal W, Okello E. Effects of the Red Bull energy drink on cognitive function and mood in healthy young volunteers. J Psychopharmacol. 2017 Feb;31(2):211-221. doi: 10.1177/0269881116681459. Epub 2016 Dec 14.

  PMID: 28168925 RESULT

• Buckenmeyer PJ, Bauer JA, Hokanson JF, Hendrick JL. Cognitive influence of a 5-h ENERGY(R) shot: Are effects perceived or real? Physiol Behav. 2015 Dec 1;152(Pt A):323-7. doi: 10.1016/j.physbeh.2015.09.003. Epub 2015 Sep 21.

  PMID: 26394126 RESULT

• Smith AP, Richards G. Energy drinks, caffeine, junk food, breakfast, depression and academic attainment of secondary school students. J Psychopharmacol. 2018 Aug;32(8):893-899. doi: 10.1177/0269881118783314. Epub 2018 Jun 27.

  PMID: 29947575 RESULT

• Brothers RM, Christmas KM, Patik JC, Bhella PS. Heart rate, blood pressure and repolarization effects of an energy drink as compared to coffee. Clin Physiol Funct Imaging. 2017 Nov;37(6):675-681. doi: 10.1111/cpf.12357. Epub 2016 Mar 1.

  PMID: 26931509 RESULT

MeSH Terms

Interventions

Energy Drinks

Intervention Hierarchy (Ancestors)

Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Syed Muhammad Ashraf Jahangeer

  Dow University of Health Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: June 28, 2021
• First Posted: July 14, 2021
• Study Start: June 29, 2021
• Primary Completion: February 28, 2022
• Study Completion: September 1, 2022
• Last Updated: September 16, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)