Comparison of the Swallowing Functions in Sarcopenia and Dynapenia

NCT04960007 | Unknown

• 1 other identifier: 261
• Study Type: observational
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients

Conditions

Sarcopenia; Dysphagia; Swallowing Disorder

Keywords

sarcopenia; dynapenia; swallowing; deglutition; dysphagia

Outcome Measures

Primary Outcomes (6)

• The values of Pharyngeal Residue Severity

  It was assessed with Fiberoptic Endoscopic Evaluation of Swallowing. Fiberoptic Endoscopic Evaluation of Swallowing results were scored on Yale Pharyngeal Residue Severity Rating scale. The scores of scale were none, trace, mild, moderate, and severe. The high-grade symptom scores were worst, low scores were good swallowing functions.

  Baseline

• The values of penetration and aspiration

  It was assessed with Fiberoptic Endoscopic Evaluation of Swallowing. Fiberoptic Endoscopic Evaluation of Swallowing results were scored on the Penetration and aspiration scale. The scores of scale were between 1-8 points. The high points were worst, low points were good swallowing functions.

  Baseline

• The evaluation of eating and swallowing functions

  They were assessed by Eating Assessment Tool in participants. Composite Score ranges from 0 ( good) to 4 (worst). The minimum total score was 0 and the maximum total score was 40. The cut-off value was 3 points. High scores show worst eating and swallowing functions, and low quality of life.

  Baseline

• The evaluation of depression

  They were assessed by Geriatric Depression Scale in participants. The scores between 0-10 were no depression, between 11-13 points were probably depression, and higher of 14 points were exact depression.

  Baseline

• The values of muscle strength

  They were assessed as newton by hand grip device.

  Baseline

• The values of muscle mass

  The diameters of tigh were measured with tailor meter by a Physical Medicine and Rehabilitation professionals (measure unit is cm).

  Baseline

Secondary Outcomes (1)

• Mean of demographic

  Baseline

Study Arms (3)

Group A

Sarcopenia patients.

Group B

Dynapenia patients.

Group C

Age and gender matched non-sarcopenia and non-dynapenia patients.

Eligibility Criteria

• Age: 60 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who were 60-90 years old.

You may qualify if:

• Age between 60-90 years
• Sarcopenia and dynapenia patients in study groups
• Non- sarcopenia and non-dynapenia patients in control groups
• Patients who were accept to consent form

You may not qualify if:

• Severe sarcopenia patients
• Cognitive limitations
• Out of age 60-90 years old
• Patients who were not accept to consent form

Sponsors & Collaborators

• Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization: lead

Study Sites (1)

Prof Dr Cemil Tascioglu City Hospital

Istanbul, 34384, Turkey (Türkiye)

Location

Related Publications (3)

• Firat Ozer F, Akin S, Soysal T, Gokcekuyu BM, Erturk Zararsiz G. Relationship Between Dysphagia and Sarcopenia with Comprehensive Geriatric Evaluation. Dysphagia. 2021 Feb;36(1):140-146. doi: 10.1007/s00455-020-10120-3. Epub 2020 Apr 27.

  PMID: 32342177 BACKGROUND

• Kara M, Kaymak B, Frontera W, Ata AM, Ricci V, Ekiz T, Chang KV, Han DS, Michail X, Quittan M, Lim JY, Bean JF, Franchignoni F, Ozcakar L. Diagnosing sarcopenia: Functional perspectives and a new algorithm from the ISarcoPRM. J Rehabil Med. 2021 Jun 21;53(6):jrm00209. doi: 10.2340/16501977-2851.

  PMID: 34121127 BACKGROUND

• Chen YC, Chen PY, Wang YC, Wang TG, Han DS. Decreased swallowing function in the sarcopenic elderly without clinical dysphagia: a cross-sectional study. BMC Geriatr. 2020 Oct 21;20(1):419. doi: 10.1186/s12877-020-01832-0.

  PMID: 33087067 BACKGROUND

MeSH Terms

Conditions

Sarcopenia; Deglutition Disorders

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Pharyngeal Diseases; Otorhinolaryngologic Diseases

Study Officials

• yavuz atar, Asso Prof,MD

  Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist, MD

Study Record Dates

• First Submitted: July 2, 2021
• First Posted: July 13, 2021
• Study Start: July 26, 2021
• Primary Completion: August 27, 2021
• Study Completion: August 27, 2021
• Last Updated: August 25, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)