NCT04952103

Brief Summary

This study is a prospective, real world study.The objective is to observe the diagnosis and first-line treatment of Chinese patients with cancer of unknown primary, and collect the clinicopathological characteristics, treatment outcomes, survival and other data of the patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2021

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 18, 2021

Completed
12 days until next milestone

First Submitted

Initial submission to the registry

June 30, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 7, 2021

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 18, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 18, 2024

Completed
Last Updated

July 7, 2021

Status Verified

June 1, 2021

Enrollment Period

2 years

First QC Date

June 30, 2021

Last Update Submit

July 6, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Progression-free survival (PFS)

    8 months

Interventions

The patient's treatment is determined by the physician in charge according to the patient's clinical situation and relevant guidelines, without additional intervention.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with cancer of unknown primary (CUP) and are gonging to receive the first-line therapy for CUP

You may qualify if:

  • Had a diagnosis of cancer of unknown primary (CUP) after a standard evaluation .
  • Prepared to receive first-line therapy for CUP

You may not qualify if:

  • Patients who had previously received systemic therapy for CUP
  • Previous history of other cancers, except cervix cancer or basal cell carcinoma of the skin that has been cured
  • The investigator considered that there were contraindications to treatment or were not appropriate to participate in this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fudan University Shanghai Cencer Center

Shanghai, Shanghai Municipality, 200032, China

RECRUITING

MeSH Terms

Conditions

Neoplasms, Unknown Primary

Condition Hierarchy (Ancestors)

Neoplasm MetastasisNeoplastic ProcessesNeoplasmsPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 30, 2021

First Posted

July 7, 2021

Study Start

June 18, 2021

Primary Completion

June 18, 2023

Study Completion

June 18, 2024

Last Updated

July 7, 2021

Record last verified: 2021-06

Locations